Interactions médicamenteuses
Insulin detemir + Insulin glargine-lixisenatide
Gravité: Majeure
Insulin detemir and Insulin glargine-lixisenatide: major interaction.
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Résumé
This combination product already contains basal insulin, so adding insulin detemir duplicates basal insulin therapy. The result is a high risk of hypoglycemia from overlapping basal coverage.
Ce que signifie cette interaction, en termes simples
Insulin detemir and Insulin glargine-lixisenatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin detemir belongs to Endocrine; Insulin glargine-lixisenatide belongs to Endocrine.
Pourquoi elle survient
Therapeutic duplication with additive insulin effect.
Conduite à tenir
Avoid using two basal insulins together; use one regimen and adjust doses to the patient's glycemic needs. If switching, stop the other basal insulin and monitor glucose closely.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Insulin glargine-lixisenatide
- Albiglutide + Insulin glargine-lixisenatide Majeure
- Chlorpropamide + Insulin glargine-lixisenatide Majeure
- Dulaglutide + Insulin glargine-lixisenatide Majeure
- Ethanol + Insulin glargine-lixisenatide Majeure
- Exenatide injectable + Insulin glargine-lixisenatide Majeure
- Glimepiride + Insulin glargine-lixisenatide Majeure
Autres interactions de Insulin detemir
Questions fréquentes
Can I take Insulin detemir with Insulin glargine-lixisenatide?
MediHelp rates the interaction as major. Insulin detemir and Insulin glargine-lixisenatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. This combination product already contains basal insulin, so adding insulin detemir duplicates basal insulin therapy. The result is a high risk of hypoglycemia from overlapping basal coverage.
How serious is the interaction between Insulin detemir and Insulin glargine-lixisenatide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using two basal insulins together; use one regimen and adjust doses to the patient's glycemic needs. If switching, stop the other basal insulin and monitor glucose closely.
What other medicines interact with Insulin glargine-lixisenatide?
MediHelp also lists interactions of Insulin glargine-lixisenatide with, for example, Albiglutide, Chlorpropamide, Dulaglutide. The full list is on the Insulin glargine-lixisenatide page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
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