दवाओं की अंतःक्रिया
Adenovirus types 4 and 7 live + Topotecan
गंभीरता: निषिद्ध
Adenovirus types 4 and 7 live and Topotecan: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Topotecan causes myelosuppression and immunosuppression, so a live oral adenovirus vaccine may replicate excessively and cause infection. The vaccine response may also be inadequate.
इस इंटरैक्शन का सरल भाषा में अर्थ
Adenovirus types 4 and 7 live and Topotecan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
ऐसा क्यों होता है
Cytotoxic immunosuppression impairs control of live attenuated virus replication and blunts vaccine-induced immunity.
क्या करें
Do not give live vaccines during chemotherapy. Defer vaccination until immune recovery, typically at least 3 months after stopping treatment, and consider non-live alternatives.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Adenovirus types 4 and 7 live और Topotecan की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Topotecan के अन्य इंटरैक्शन
- Amiodarone + Topotecan गंभीर
- Cisplatin + Topotecan गंभीर
- Cobicistat + Topotecan गंभीर
- Cyclosporine + Topotecan गंभीर
- Cyclosporin + Topotecan गंभीर
- Darunavir + Topotecan गंभीर
अक्सर पूछे जाने वाले प्रश्न
Can I take Adenovirus types 4 and 7 live with Topotecan?
MediHelp rates the interaction as contraindicated. Adenovirus types 4 and 7 live and Topotecan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Topotecan causes myelosuppression and immunosuppression, so a live oral adenovirus vaccine may replicate excessively and cause infection. The vaccine response may also be inadequate.
How serious is the interaction between Adenovirus types 4 and 7 live and Topotecan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines during chemotherapy. Defer vaccination until immune recovery, typically at least 3 months after stopping treatment, and consider non-live alternatives.
What other medicines interact with Topotecan?
MediHelp also lists interactions of Topotecan with, for example, Amiodarone, Cisplatin, Cobicistat. The full list is on the Topotecan page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
