दवाओं की अंतःक्रिया
Cisplatin + Topotecan
गंभीरता: गंभीर
Cisplatin and Topotecan: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Cisplatin and topotecan both suppress bone marrow, and together they produce more severe neutropenia and thrombocytopenia than either drug alone. Myelosuppression can be dose-limiting and may lead to infection or bleeding.
इस इंटरैक्शन का सरल भाषा में अर्थ
Cisplatin and Topotecan can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Cisplatin belongs to Oncology; Topotecan belongs to Oncology.
ऐसा क्यों होता है
Additive pharmacodynamic myelosuppression, with possible sequence-dependent enhancement of toxicity.
क्या करें
Monitor complete blood counts frequently and reduce topotecan dose or delay cycles for severe cytopenias. Follow established regimen sequencing and use growth factor support when indicated.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Cisplatin और Topotecan की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Cisplatin के अन्य इंटरैक्शन
Topotecan के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Cisplatin with Topotecan?
MediHelp rates the interaction as major. Cisplatin and Topotecan can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cisplatin and topotecan both suppress bone marrow, and together they produce more severe neutropenia and thrombocytopenia than either drug alone. Myelosuppression can be dose-limiting and may lead to infection or bleeding.
How serious is the interaction between Cisplatin and Topotecan?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor complete blood counts frequently and reduce topotecan dose or delay cycles for severe cytopenias. Follow established regimen sequencing and use growth factor support when indicated.
What other medicines interact with Cisplatin?
MediHelp also lists interactions of Cisplatin with, for example, Cidofovir, Adefovir, Adenovirus types 4 and 7 live. The full list is on the Cisplatin page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
