दवाओं की अंतःक्रिया
Amiloride + Amlodipine-olmesartan-hydrochlorothiazide
गंभीरता: गंभीर
Amiloride and Amlodipine-olmesartan-hydrochlorothiazide: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Olmesartan and amiloride both reduce potassium excretion and can cause hyperkalemia, which hydrochlorothiazide only partly offsets. The risk is highest with renal impairment, diabetes or older age.
इस इंटरैक्शन का सरल भाषा में अर्थ
Amiloride and Amlodipine-olmesartan-hydrochlorothiazide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amiloride belongs to Cardiovascular; Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular.
ऐसा क्यों होता है
Additive reduction of renal potassium excretion by angiotensin receptor blockade and ENaC inhibition, partly opposed by thiazide kaliuresis.
क्या करें
Monitor serum potassium and renal function soon after starting and periodically thereafter. Stop amiloride and avoid potassium supplements if hyperkalemia develops.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Amiloride और Amlodipine-olmesartan-hydrochlorothiazide की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Amlodipine-olmesartan-hydrochlorothiazide के अन्य इंटरैक्शन
- Aliskiren + Amlodipine-olmesartan-hydrochlorothiazide निषिद्ध
- Amlodipine-olmesartan-hydrochlorothiazide + Dofetilide निषिद्ध
- Amlodipine-olmesartan-hydrochlorothiazide + Sparsentan निषिद्ध
- Acemetacin + Amlodipine-olmesartan-hydrochlorothiazide गंभीर
- Aldesleukin + Amlodipine-olmesartan-hydrochlorothiazide गंभीर
- Amifostine + Amlodipine-olmesartan-hydrochlorothiazide गंभीर
Amiloride के अन्य इंटरैक्शन
- Amiloride + Eplerenone निषिद्ध
- Amiloride + Spironolactone निषिद्ध
- Amiloride + Triamterene निषिद्ध
- Aceclofenac + Amiloride गंभीर
- Acemetacin + Amiloride गंभीर
- Amiloride + Amlodipine-benazepril गंभीर
अक्सर पूछे जाने वाले प्रश्न
Can I take Amiloride with Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp rates the interaction as major. Amiloride and Amlodipine-olmesartan-hydrochlorothiazide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Olmesartan and amiloride both reduce potassium excretion and can cause hyperkalemia, which hydrochlorothiazide only partly offsets. The risk is highest with renal impairment, diabetes or older age.
How serious is the interaction between Amiloride and Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and renal function soon after starting and periodically thereafter. Stop amiloride and avoid potassium supplements if hyperkalemia develops.
What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.
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