दवाओं की अंतःक्रिया
Amlodipine-olmesartan-hydrochlorothiazide + Benazepril
गंभीरता: गंभीर
Amlodipine-olmesartan-hydrochlorothiazide and Benazepril: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Combining an angiotensin receptor blocker with an ACE inhibitor produces dual blockade of the renin-angiotensin system. This raises the risk of hypotension, hyperkalemia and acute kidney injury, and outcome trials showed no cardiovascular benefit over a single agent in most patients.
इस इंटरैक्शन का सरल भाषा में अर्थ
Amlodipine-olmesartan-hydrochlorothiazide and Benazepril can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Benazepril belongs to Cardiovascular.
ऐसा क्यों होता है
Additive pharmacodynamic inhibition of the renin-angiotensin-aldosterone system at two sites, which reduces glomerular filtration pressure and aldosterone-mediated potassium excretion.
क्या करें
Avoid the combination and use only one RAS blocker. If it is unavoidable, monitor serum potassium, creatinine and blood pressure closely.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Amlodipine-olmesartan-hydrochlorothiazide और Benazepril की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Amlodipine-olmesartan-hydrochlorothiazide के अन्य इंटरैक्शन
- Aliskiren + Amlodipine-olmesartan-hydrochlorothiazide निषिद्ध
- Amlodipine-olmesartan-hydrochlorothiazide + Dofetilide निषिद्ध
- Amlodipine-olmesartan-hydrochlorothiazide + Sparsentan निषिद्ध
- Acemetacin + Amlodipine-olmesartan-hydrochlorothiazide गंभीर
- Aldesleukin + Amlodipine-olmesartan-hydrochlorothiazide गंभीर
- Amifostine + Amlodipine-olmesartan-hydrochlorothiazide गंभीर
Benazepril के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Amlodipine-olmesartan-hydrochlorothiazide with Benazepril?
MediHelp rates the interaction as major. Amlodipine-olmesartan-hydrochlorothiazide and Benazepril can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Combining an angiotensin receptor blocker with an ACE inhibitor produces dual blockade of the renin-angiotensin system. This raises the risk of hypotension, hyperkalemia and acute kidney injury, and outcome trials showed no cardiovascular benefit over a single agent in most patients.
How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Benazepril?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and use only one RAS blocker. If it is unavoidable, monitor serum potassium, creatinine and blood pressure closely.
What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
