दवाओं की अंतःक्रिया
Amlodipine-hydrochlorothiazide-valsartan + Benazepril
गंभीरता: गंभीर
Amlodipine-hydrochlorothiazide-valsartan and Benazepril: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Adding an ACE inhibitor to a regimen already containing the angiotensin receptor blocker valsartan produces dual renin-angiotensin system blockade. This raises the risk of symptomatic hypotension, hyperkalemia and acute kidney injury without a meaningful cardiovascular benefit in most patients.
इस इंटरैक्शन का सरल भाषा में अर्थ
Amlodipine-hydrochlorothiazide-valsartan and Benazepril can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amlodipine-hydrochlorothiazide-valsartan belongs to Cardiovascular; Benazepril belongs to Cardiovascular.
ऐसा क्यों होता है
Additive pharmacodynamic inhibition of the renin-angiotensin-aldosterone system at two different points, reducing glomerular filtration pressure and aldosterone-mediated potassium excretion.
क्या करें
Avoid the combination and use a single renin-angiotensin agent. If it is unavoidable, monitor blood pressure, serum potassium and creatinine closely.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Amlodipine-hydrochlorothiazide-valsartan और Benazepril की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Amlodipine-hydrochlorothiazide-valsartan के अन्य इंटरैक्शन
- Aliskiren + Amlodipine-hydrochlorothiazide-valsartan निषिद्ध
- Amlodipine-hydrochlorothiazide-valsartan + Dofetilide निषिद्ध
- Amlodipine-hydrochlorothiazide-valsartan + Sparsentan निषिद्ध
- Aceclofenac + Amlodipine-hydrochlorothiazide-valsartan गंभीर
- Aldesleukin + Amlodipine-hydrochlorothiazide-valsartan गंभीर
- Amifostine + Amlodipine-hydrochlorothiazide-valsartan गंभीर
Benazepril के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Amlodipine-hydrochlorothiazide-valsartan with Benazepril?
MediHelp rates the interaction as major. Amlodipine-hydrochlorothiazide-valsartan and Benazepril can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Adding an ACE inhibitor to a regimen already containing the angiotensin receptor blocker valsartan produces dual renin-angiotensin system blockade. This raises the risk of symptomatic hypotension, hyperkalemia and acute kidney injury without a meaningful cardiovascular benefit in most patients.
How serious is the interaction between Amlodipine-hydrochlorothiazide-valsartan and Benazepril?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and use a single renin-angiotensin agent. If it is unavoidable, monitor blood pressure, serum potassium and creatinine closely.
What other medicines interact with Amlodipine-hydrochlorothiazide-valsartan?
MediHelp also lists interactions of Amlodipine-hydrochlorothiazide-valsartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-hydrochlorothiazide-valsartan page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
