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Amlodipine-olmesartan-hydrochlorothiazide + Calcium carbonate

गंभीरता: मध्यम

Amlodipine-olmesartan-hydrochlorothiazide and Calcium carbonate: moderate interaction.

अंतिम अपडेट

केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।

इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।

सारांश

Calcium salts can reduce the effect of calcium channel blockers in cases of high-dose or intravenous calcium, but oral calcium carbonate has little effect on amlodipine. Thiazides reduce urinary calcium excretion, so with large calcium carbonate doses there is a risk of hypercalcemia and milk-alkali syndrome.

इस इंटरैक्शन का सरल भाषा में अर्थ

Amlodipine-olmesartan-hydrochlorothiazide and Calcium carbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Calcium carbonate belongs to Gastrointestinal Tract.

साक्ष्य स्तर: Moderate

ऐसा क्यों होता है

Thiazide-reduced renal calcium excretion combined with calcium load, with minimal pharmacodynamic antagonism of amlodipine at oral doses.

क्या करें

Monitor serum calcium in patients taking regular or high-dose calcium supplements or antacids. Reduce calcium dose if hypercalcemia occurs.

फार्मासिस्ट से क्या पूछें

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ सदस्यों के लिए

पूरा पेज खोलें

Amlodipine-olmesartan-hydrochlorothiazide और Calcium carbonate की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।

अक्सर पूछे जाने वाले प्रश्न

Can I take Amlodipine-olmesartan-hydrochlorothiazide with Calcium carbonate?

MediHelp rates the interaction as moderate. Amlodipine-olmesartan-hydrochlorothiazide and Calcium carbonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Calcium salts can reduce the effect of calcium channel blockers in cases of high-dose or intravenous calcium, but oral calcium carbonate has little effect on amlodipine. Thiazides reduce urinary calcium excretion, so with large calcium carbonate doses there is a risk of hypercalcemia and milk-alkali syndrome.

How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Calcium carbonate?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium in patients taking regular or high-dose calcium supplements or antacids. Reduce calcium dose if hypercalcemia occurs.

What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?

MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.

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