दवाओं की अंतःक्रिया
Amlodipine-olmesartan-hydrochlorothiazide + Canagliflozin
गंभीरता: मध्यम
Amlodipine-olmesartan-hydrochlorothiazide and Canagliflozin: moderate interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Canagliflozin causes osmotic diuresis and can add to the volume depletion and blood pressure lowering of an ARB and thiazide, with a risk of hypotension and acute kidney injury. Canagliflozin may also modestly increase potassium in some patients, especially with an ARB and renal impairment.
इस इंटरैक्शन का सरल भाषा में अर्थ
Amlodipine-olmesartan-hydrochlorothiazide and Canagliflozin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Canagliflozin belongs to Endocrine.
ऐसा क्यों होता है
Additive diuretic and hypotensive effects, with possible additive effects on potassium and renal hemodynamics.
क्या करें
Assess volume status before starting canagliflozin and consider reducing the diuretic dose. Monitor blood pressure, renal function and potassium.
फार्मासिस्ट से क्या पूछें
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Amlodipine-olmesartan-hydrochlorothiazide और Canagliflozin की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 7 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Amlodipine-olmesartan-hydrochlorothiazide के अन्य इंटरैक्शन
- Aliskiren + Amlodipine-olmesartan-hydrochlorothiazide निषिद्ध
- Amlodipine-olmesartan-hydrochlorothiazide + Dofetilide निषिद्ध
- Amlodipine-olmesartan-hydrochlorothiazide + Sparsentan निषिद्ध
- Acemetacin + Amlodipine-olmesartan-hydrochlorothiazide गंभीर
- Aldesleukin + Amlodipine-olmesartan-hydrochlorothiazide गंभीर
- Amifostine + Amlodipine-olmesartan-hydrochlorothiazide गंभीर
Canagliflozin के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Amlodipine-olmesartan-hydrochlorothiazide with Canagliflozin?
MediHelp rates the interaction as moderate. Amlodipine-olmesartan-hydrochlorothiazide and Canagliflozin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Canagliflozin causes osmotic diuresis and can add to the volume depletion and blood pressure lowering of an ARB and thiazide, with a risk of hypotension and acute kidney injury. Canagliflozin may also modestly increase potassium in some patients, especially with an ARB and renal impairment.
How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Canagliflozin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Assess volume status before starting canagliflozin and consider reducing the diuretic dose. Monitor blood pressure, renal function and potassium.
What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.
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