दवाओं की अंतःक्रिया
Amoxicillin-clavulanic acid + Pretomanid
गंभीरता: गंभीर
Amoxicillin-clavulanic acid and Pretomanid: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
The pretomanid-containing regimen is associated with hepatotoxicity, and labeling advises avoiding other hepatotoxic agents. Amoxicillin-clavulanate can cause cholestatic or mixed liver injury. Concurrent use could raise the risk of serious hepatic injury.
इस इंटरैक्शन का सरल भाषा में अर्थ
Amoxicillin-clavulanic acid and Pretomanid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amoxicillin-clavulanic acid belongs to Anti Bacterial; Pretomanid belongs to Anti Bacterial.
ऐसा क्यों होता है
Additive hepatotoxicity from pretomanid-based therapy and clavulanate-associated liver injury.
क्या करें
Avoid amoxicillin-clavulanate during pretomanid therapy and select a less hepatotoxic antibiotic. If it cannot be avoided, monitor liver function tests frequently.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Amoxicillin-clavulanic acid और Pretomanid की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Amoxicillin-clavulanic acid के अन्य इंटरैक्शन
Pretomanid के अन्य इंटरैक्शन
- Amiodarone + Pretomanid गंभीर
- Amobarbital + Pretomanid गंभीर
- Apalutamide + Pretomanid गंभीर
- Armodafinil + Pretomanid गंभीर
- Azathioprine + Pretomanid गंभीर
- Bosentan + Pretomanid गंभीर
अक्सर पूछे जाने वाले प्रश्न
Can I take Amoxicillin-clavulanic acid with Pretomanid?
MediHelp rates the interaction as major. Amoxicillin-clavulanic acid and Pretomanid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. The pretomanid-containing regimen is associated with hepatotoxicity, and labeling advises avoiding other hepatotoxic agents. Amoxicillin-clavulanate can cause cholestatic or mixed liver injury. Concurrent use could raise the risk of serious hepatic injury.
How serious is the interaction between Amoxicillin-clavulanic acid and Pretomanid?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid amoxicillin-clavulanate during pretomanid therapy and select a less hepatotoxic antibiotic. If it cannot be avoided, monitor liver function tests frequently.
What other medicines interact with Amoxicillin-clavulanic acid?
MediHelp also lists interactions of Amoxicillin-clavulanic acid with, for example, Methotrexate, Pexidartinib, Allopurinol. The full list is on the Amoxicillin-clavulanic acid page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
