दवाओं की अंतःक्रिया
Amphotericin b deoxycholate + Colistin
गंभीरता: गंभीर
Amphotericin b deoxycholate and Colistin: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Both drugs are nephrotoxic, and using them together increases the chance of acute kidney injury. Colistin also carries neurotoxic effects, and renal impairment raises its exposure further.
इस इंटरैक्शन का सरल भाषा में अर्थ
Amphotericin b deoxycholate and Colistin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
ऐसा क्यों होता है
Additive direct tubular toxicity and renal vasoconstriction.
क्या करें
Avoid concurrent use if alternatives exist; otherwise monitor serum creatinine and electrolytes frequently, keep patients well hydrated and adjust colistin dose to renal function.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Amphotericin b deoxycholate और Colistin की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Colistin के अन्य इंटरैक्शन
- Colistin + Polymyxin b निषिद्ध
- Amikacin + Colistin गंभीर
- Amphotericin b + Colistin गंभीर
- Atracurium + Colistin गंभीर
- Bacitracin + Colistin गंभीर
- Capreomycin + Colistin गंभीर
अक्सर पूछे जाने वाले प्रश्न
Can I take Amphotericin b deoxycholate with Colistin?
MediHelp rates the interaction as major. Amphotericin b deoxycholate and Colistin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs are nephrotoxic, and using them together increases the chance of acute kidney injury. Colistin also carries neurotoxic effects, and renal impairment raises its exposure further.
How serious is the interaction between Amphotericin b deoxycholate and Colistin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use if alternatives exist; otherwise monitor serum creatinine and electrolytes frequently, keep patients well hydrated and adjust colistin dose to renal function.
What other medicines interact with Colistin?
MediHelp also lists interactions of Colistin with, for example, Polymyxin b, Amikacin, Amphotericin b. The full list is on the Colistin page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
