दवाओं की अंतःक्रिया
Aripiprazole + Oliceridine
गंभीरता: गंभीर
Aripiprazole and Oliceridine: major interaction.
अंतिम अपडेट स्रोत: UK SmPC
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Oliceridine is an opioid that causes sedation and respiratory depression, and aripiprazole adds CNS depressant effects. Oliceridine is also partly metabolized by CYP3A4 and CYP2D6, which aripiprazole does not substantially affect, so the main concern is additive depression.
इस इंटरैक्शन का सरल भाषा में अर्थ
Aripiprazole and Oliceridine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Aripiprazole belongs to Central Nervous System; Oliceridine belongs to Musculoskeletal.
ऐसा क्यों होता है
Additive CNS and respiratory depression between an opioid and an antipsychotic.
क्या करें
Reserve combined use for patients without adequate alternatives, using the lowest oliceridine dose for the shortest duration. Monitor sedation and respiratory rate closely.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Aripiprazole और Oliceridine की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 7 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
संदर्भ
- Abilify 1 mg/mL Oral Solution - SmPC sections 4.3/4.5 (class statement: other CNS medicinal products with overlapping adverse reactions such as sedation; "caution should be used when aripiprazole is administered in combination with alcohol or other CNS medicinal products with overlapping adverse re… — electronic medicines compendium (UK SmPC)
Aripiprazole के अन्य इंटरैक्शन
Oliceridine के अन्य इंटरैक्शन
- Isocarboxazid + Oliceridine निषिद्ध
- Alprazolam + Oliceridine गंभीर
- Amiodarone + Oliceridine गंभीर
- Amisulpride + Oliceridine गंभीर
- Amitriptyline + Oliceridine गंभीर
- Amobarbital + Oliceridine गंभीर
अक्सर पूछे जाने वाले प्रश्न
Can I take Aripiprazole with Oliceridine?
MediHelp rates the interaction as major. Aripiprazole and Oliceridine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oliceridine is an opioid that causes sedation and respiratory depression, and aripiprazole adds CNS depressant effects. Oliceridine is also partly metabolized by CYP3A4 and CYP2D6, which aripiprazole does not substantially affect, so the main concern is additive depression.
How serious is the interaction between Aripiprazole and Oliceridine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Reserve combined use for patients without adequate alternatives, using the lowest oliceridine dose for the shortest duration. Monitor sedation and respiratory rate closely.
What other medicines interact with Aripiprazole?
MediHelp also lists interactions of Aripiprazole with, for example, Pimozide, Thioridazine, Amisulpride. The full list is on the Aripiprazole page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
