दवाओं की अंतःक्रिया
Azathioprine + Olaparib
गंभीरता: गंभीर
Azathioprine and Olaparib: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Both drugs suppress bone marrow function, and combining them may deepen or prolong anemia, neutropenia and thrombocytopenia. This raises the risk of infection and bleeding.
इस इंटरैक्शन का सरल भाषा में अर्थ
Azathioprine and Olaparib can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Azathioprine belongs to Gastrointestinal Tract; Olaparib belongs to Oncology.
ऐसा क्यों होता है
Additive myelosuppression, with azathioprine impairing purine synthesis and olaparib inhibiting PARP and causing DNA damage in hematopoietic cells.
क्या करें
Monitor complete blood counts frequently, especially in the first months of combined therapy. Reduce the dose of one or both drugs or interrupt therapy if cytopenias develop.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Azathioprine और Olaparib की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Azathioprine के अन्य इंटरैक्शन
- Adenovirus types 4 and 7 live + Azathioprine निषिद्ध
- Azathioprine + Bcg vaccine live निषिद्ध
- Azathioprine + Febuxostat निषिद्ध
- Azathioprine + Influenza virus vaccine quadrivalent intranasal निषिद्ध
- Azathioprine + Measles mumps and rubella vaccine निषिद्ध
- Azathioprine + Measles mumps and rubella vaccine live निषिद्ध
Olaparib के अन्य इंटरैक्शन
- Amiodarone + Olaparib गंभीर
- Amobarbital + Olaparib गंभीर
- Apalutamide + Olaparib गंभीर
- Aprepitant + Olaparib गंभीर
- Carbamazepine + Olaparib गंभीर
- Carboplatin + Olaparib गंभीर
अक्सर पूछे जाने वाले प्रश्न
Can I take Azathioprine with Olaparib?
MediHelp rates the interaction as major. Azathioprine and Olaparib can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs suppress bone marrow function, and combining them may deepen or prolong anemia, neutropenia and thrombocytopenia. This raises the risk of infection and bleeding.
How serious is the interaction between Azathioprine and Olaparib?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor complete blood counts frequently, especially in the first months of combined therapy. Reduce the dose of one or both drugs or interrupt therapy if cytopenias develop.
What other medicines interact with Azathioprine?
MediHelp also lists interactions of Azathioprine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Febuxostat. The full list is on the Azathioprine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
