दवाओं की अंतःक्रिया
Bromocriptine + Cobicistat
गंभीरता: गंभीर
Bromocriptine and Cobicistat: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Cobicistat is a strong CYP3A4 inhibitor and may considerably raise bromocriptine exposure. This can cause nausea, hypotension, syncope and other dopaminergic effects, and ergot-related toxicity is a concern with potent CYP3A4 inhibitors.
इस इंटरैक्शन का सरल भाषा में अर्थ
Bromocriptine and Cobicistat can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Bromocriptine belongs to Central Nervous System; Cobicistat belongs to Miscellaneous.
ऐसा क्यों होता है
Inhibition of CYP3A4-mediated bromocriptine metabolism by cobicistat.
क्या करें
Start with a low bromocriptine dose and titrate carefully, or choose an alternative dopamine agonist. Monitor blood pressure and for signs of ergot toxicity.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Bromocriptine और Cobicistat की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 7 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Bromocriptine के अन्य इंटरैक्शन
Cobicistat के अन्य इंटरैक्शन
- Alfuzosin + Cobicistat निषिद्ध
- Apalutamide + Cobicistat निषिद्ध
- Cobicistat + Colchicine निषिद्ध
- Cobicistat + Dronedarone निषिद्ध
- Cobicistat + Eletriptan निषिद्ध
- Cobicistat + Eplerenone निषिद्ध
अक्सर पूछे जाने वाले प्रश्न
Can I take Bromocriptine with Cobicistat?
MediHelp rates the interaction as major. Bromocriptine and Cobicistat can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cobicistat is a strong CYP3A4 inhibitor and may considerably raise bromocriptine exposure. This can cause nausea, hypotension, syncope and other dopaminergic effects, and ergot-related toxicity is a concern with potent CYP3A4 inhibitors.
How serious is the interaction between Bromocriptine and Cobicistat?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Start with a low bromocriptine dose and titrate carefully, or choose an alternative dopamine agonist. Monitor blood pressure and for signs of ergot toxicity.
What other medicines interact with Bromocriptine?
MediHelp also lists interactions of Bromocriptine with, for example, Amisulpride, Atazanavir, Darunavir. The full list is on the Bromocriptine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
