दवाओं की अंतःक्रिया
Bumetanide + Captopril-hydrochlorothiazide
गंभीरता: गंभीर
Bumetanide and Captopril-hydrochlorothiazide: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Combining a loop diuretic with a thiazide produces sequential nephron blockade, causing marked diuresis, hypokalemia, hyponatremia, hypomagnesemia and volume depletion. With captopril, hypotension and acute kidney injury are more likely.
इस इंटरैक्शन का सरल भाषा में अर्थ
Bumetanide and Captopril-hydrochlorothiazide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Bumetanide belongs to Cardiovascular; Captopril-hydrochlorothiazide belongs to Cardiovascular.
ऐसा क्यों होता है
Additive natriuresis and potassium wasting at different nephron sites, with volume depletion potentiating ACE inhibitor hypotension and renal effects.
क्या करें
Monitor electrolytes, creatinine, weight and blood pressure closely, particularly in the first weeks. Reduce diuretic doses or replace potassium and magnesium as needed.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Bumetanide और Captopril-hydrochlorothiazide की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Captopril-hydrochlorothiazide के अन्य इंटरैक्शन
- Aliskiren + Captopril-hydrochlorothiazide निषिद्ध
- Captopril-hydrochlorothiazide + Dofetilide निषिद्ध
- Captopril-hydrochlorothiazide + Sacubitril / valsartan निषिद्ध
- Aceclofenac + Captopril-hydrochlorothiazide गंभीर
- Aldesleukin + Captopril-hydrochlorothiazide गंभीर
- Amifostine + Captopril-hydrochlorothiazide गंभीर
Bumetanide के अन्य इंटरैक्शन
- Amifostine + Bumetanide गंभीर
- Amikacin + Bumetanide गंभीर
- Bumetanide + Carbenoxolone गंभीर
- Bumetanide + Cisplatin गंभीर
- Bumetanide + Digoxin गंभीर
- Bumetanide + Ethacrynic acid गंभीर
अक्सर पूछे जाने वाले प्रश्न
Can I take Bumetanide with Captopril-hydrochlorothiazide?
MediHelp rates the interaction as major. Bumetanide and Captopril-hydrochlorothiazide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Combining a loop diuretic with a thiazide produces sequential nephron blockade, causing marked diuresis, hypokalemia, hyponatremia, hypomagnesemia and volume depletion. With captopril, hypotension and acute kidney injury are more likely.
How serious is the interaction between Bumetanide and Captopril-hydrochlorothiazide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor electrolytes, creatinine, weight and blood pressure closely, particularly in the first weeks. Reduce diuretic doses or replace potassium and magnesium as needed.
What other medicines interact with Captopril-hydrochlorothiazide?
MediHelp also lists interactions of Captopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sacubitril / valsartan. The full list is on the Captopril-hydrochlorothiazide page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
