दवाओं की अंतःक्रिया
Bupropion-naltrexone + Phenelzine
गंभीरता: निषिद्ध
Bupropion-naltrexone and Phenelzine: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Phenelzine (an irreversible non-selective MAO inhibitor) slows catecholamine breakdown, while bupropion blocks reuptake of dopamine and noradrenaline. The combination can produce hypertensive crisis, agitation and seizures; labelling for bupropion prohibits concurrent MAOI therapy.
इस इंटरैक्शन का सरल भाषा में अर्थ
Bupropion-naltrexone and Phenelzine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Bupropion-naltrexone belongs to Miscellaneous; Phenelzine belongs to Central Nervous System.
ऐसा क्यों होता है
MAO inhibition combined with dopamine and noradrenaline reuptake inhibition causes excess catecholamine activity
क्या करें
Do not use together. Wait at least 14 days after stopping phenelzine before starting the other drug; allow at least a week after stopping bupropion before starting an MAOI.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Bupropion-naltrexone और Phenelzine की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Bupropion-naltrexone के अन्य इंटरैक्शन
Phenelzine के अन्य इंटरैक्शन
- 5-HTP + Phenelzine निषिद्ध
- Amitriptyline + Phenelzine निषिद्ध
- Amoxapine + Phenelzine निषिद्ध
- Atomoxetine + Phenelzine निषिद्ध
- Benzphetamine + Phenelzine निषिद्ध
- Brimonidine + Phenelzine निषिद्ध
अक्सर पूछे जाने वाले प्रश्न
Can I take Bupropion-naltrexone with Phenelzine?
MediHelp rates the interaction as contraindicated. Bupropion-naltrexone and Phenelzine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Phenelzine (an irreversible non-selective MAO inhibitor) slows catecholamine breakdown, while bupropion blocks reuptake of dopamine and noradrenaline. The combination can produce hypertensive crisis, agitation and seizures; labelling for bupropion prohibits concurrent MAOI therapy.
How serious is the interaction between Bupropion-naltrexone and Phenelzine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together. Wait at least 14 days after stopping phenelzine before starting the other drug; allow at least a week after stopping bupropion before starting an MAOI.
What other medicines interact with Bupropion-naltrexone?
MediHelp also lists interactions of Bupropion-naltrexone with, for example, Hydrocodone, Hydromorphone, Isocarboxazid. The full list is on the Bupropion-naltrexone page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
