दवाओं की अंतःक्रिया
Clonidine + Guanfacine
गंभीरता: गंभीर
Clonidine and Guanfacine: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Both are central alpha-2 adrenergic agonists, so combining them duplicates therapy and increases the risk of hypotension, bradycardia and sedation. Patients with conduction disease may be at greater risk of heart block.
इस इंटरैक्शन का सरल भाषा में अर्थ
Clonidine and Guanfacine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Clonidine belongs to Cardiovascular; Guanfacine belongs to Cardiovascular.
ऐसा क्यों होता है
Additive central alpha-2 agonism reduces sympathetic outflow, causing pharmacodynamic synergism.
क्या करें
Avoid using both together unless there is a clear indication; if used, monitor heart rate, blood pressure and sedation closely. Taper one agent gradually when stopping to avoid rebound hypertension.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Clonidine और Guanfacine की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Clonidine के अन्य इंटरैक्शन
- Acebutolol + Clonidine गंभीर
- Amifostine + Clonidine गंभीर
- Amiodarone + Clonidine गंभीर
- Amoxapine + Clonidine गंभीर
- Atenolol-chlorthalidone + Clonidine गंभीर
- Atenolol + Clonidine गंभीर
Guanfacine के अन्य इंटरैक्शन
- Guanfacine + Lofexidine गंभीर
- Aldesleukin + Guanfacine मध्यम
- Amiodarone + Guanfacine मध्यम
- Amisulpride + Guanfacine मध्यम
- Amitriptyline + Guanfacine मध्यम
- Amobarbital + Guanfacine मध्यम
अक्सर पूछे जाने वाले प्रश्न
Can I take Clonidine with Guanfacine?
MediHelp rates the interaction as major. Clonidine and Guanfacine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both are central alpha-2 adrenergic agonists, so combining them duplicates therapy and increases the risk of hypotension, bradycardia and sedation. Patients with conduction disease may be at greater risk of heart block.
How serious is the interaction between Clonidine and Guanfacine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using both together unless there is a clear indication; if used, monitor heart rate, blood pressure and sedation closely. Taper one agent gradually when stopping to avoid rebound hypertension.
What other medicines interact with Clonidine?
MediHelp also lists interactions of Clonidine with, for example, Acebutolol, Amifostine, Amiodarone. The full list is on the Clonidine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
