दवाओं की अंतःक्रिया
Guanfacine + Lofexidine
गंभीरता: गंभीर
Guanfacine and Lofexidine: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Both drugs are central alpha-2 adrenergic agonists that lower blood pressure and heart rate. Taking them together duplicates therapy and can cause marked hypotension, bradycardia, sedation and syncope.
इस इंटरैक्शन का सरल भाषा में अर्थ
Guanfacine and Lofexidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Guanfacine belongs to Cardiovascular; Lofexidine belongs to Central Nervous System.
ऐसा क्यों होता है
Duplicate central alpha-2 agonism producing additive sympatholytic, hypotensive and bradycardic effects.
क्या करें
Avoid concurrent use where possible and choose one alpha-2 agonist. If both are required, monitor blood pressure and heart rate closely and reduce doses as needed.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Guanfacine और Lofexidine की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Lofexidine के अन्य इंटरैक्शन
- Adagrasib + Lofexidine गंभीर
- Alfuzosin + Lofexidine गंभीर
- Amiodarone + Lofexidine गंभीर
- Amisulpride + Lofexidine गंभीर
- Anagrelide + Lofexidine गंभीर
- Apomorphine + Lofexidine गंभीर
Guanfacine के अन्य इंटरैक्शन
- Clonidine + Guanfacine गंभीर
- Aldesleukin + Guanfacine मध्यम
- Amiodarone + Guanfacine मध्यम
- Amisulpride + Guanfacine मध्यम
- Amitriptyline + Guanfacine मध्यम
- Amobarbital + Guanfacine मध्यम
अक्सर पूछे जाने वाले प्रश्न
Can I take Guanfacine with Lofexidine?
MediHelp rates the interaction as major. Guanfacine and Lofexidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs are central alpha-2 adrenergic agonists that lower blood pressure and heart rate. Taking them together duplicates therapy and can cause marked hypotension, bradycardia, sedation and syncope.
How serious is the interaction between Guanfacine and Lofexidine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use where possible and choose one alpha-2 agonist. If both are required, monitor blood pressure and heart rate closely and reduce doses as needed.
What other medicines interact with Lofexidine?
MediHelp also lists interactions of Lofexidine with, for example, Adagrasib, Alfuzosin, Amiodarone. The full list is on the Lofexidine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
