दवाओं की अंतःक्रिया
Darunavir + Eletriptan
गंभीरता: निषिद्ध
Darunavir and Eletriptan: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Darunavir, usually boosted with ritonavir or cobicistat, strongly inhibits CYP3A4 and can greatly raise eletriptan exposure. This increases the risk of serious vasoconstrictive effects. Eletriptan labeling contraindicates use within 72 hours of potent CYP3A4 inhibitors.
इस इंटरैक्शन का सरल भाषा में अर्थ
Darunavir and Eletriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Darunavir belongs to Anti Virals; Eletriptan belongs to Central Nervous System.
ऐसा क्यों होता है
Potent inhibition of CYP3A4-mediated eletriptan metabolism, mainly via the ritonavir or cobicistat booster.
क्या करें
Do not give eletriptan within 72 hours of boosted darunavir. Use a triptan that is not metabolized by CYP3A4, such as sumatriptan or rizatriptan.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Darunavir और Eletriptan की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Eletriptan के अन्य इंटरैक्शन
- Almotriptan + Eletriptan निषिद्ध
- Atazanavir + Eletriptan निषिद्ध
- Ceritinib + Eletriptan निषिद्ध
- Clarithromycin + Eletriptan निषिद्ध
- Cobicistat + Eletriptan निषिद्ध
- Conivaptan + Eletriptan निषिद्ध
Darunavir के अन्य इंटरैक्शन
- Alfuzosin + Darunavir निषिद्ध
- Avanafil + Darunavir निषिद्ध
- Darunavir + Dronedarone निषिद्ध
- Darunavir + Ergotamine निषिद्ध
- Darunavir + Flibanserin निषिद्ध
- Darunavir + Fluticasone-salmeterol निषिद्ध
अक्सर पूछे जाने वाले प्रश्न
Can I take Darunavir with Eletriptan?
MediHelp rates the interaction as contraindicated. Darunavir and Eletriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Darunavir, usually boosted with ritonavir or cobicistat, strongly inhibits CYP3A4 and can greatly raise eletriptan exposure. This increases the risk of serious vasoconstrictive effects. Eletriptan labeling contraindicates use within 72 hours of potent CYP3A4 inhibitors.
How serious is the interaction between Darunavir and Eletriptan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give eletriptan within 72 hours of boosted darunavir. Use a triptan that is not metabolized by CYP3A4, such as sumatriptan or rizatriptan.
What other medicines interact with Eletriptan?
MediHelp also lists interactions of Eletriptan with, for example, Almotriptan, Atazanavir, Ceritinib. The full list is on the Eletriptan page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
