दवाओं की अंतःक्रिया
Defibrotide + Edoxaban
गंभीरता: निषिद्ध
Defibrotide and Edoxaban: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Defibrotide has profibrinolytic and antithrombotic activity and may add to the bleeding risk of anticoagulants such as edoxaban. Defibrotide labeling contraindicates concomitant systemic anticoagulants or fibrinolytics. Serious hemorrhage is the concern.
इस इंटरैक्शन का सरल भाषा में अर्थ
Defibrotide and Edoxaban are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Defibrotide belongs to Cardiovascular; Edoxaban belongs to Cardiovascular.
ऐसा क्यों होता है
Additive pharmacodynamic effects on hemostasis from factor Xa inhibition and defibrotide's profibrinolytic activity.
क्या करें
Do not co-administer; hold edoxaban while defibrotide is being given. Resume anticoagulation only after defibrotide therapy is finished and bleeding risk has been reassessed.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Defibrotide और Edoxaban की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Edoxaban के अन्य इंटरैक्शन
- Apixaban + Edoxaban निषिद्ध
- Edoxaban + Ketorolac निषिद्ध
- Abciximab + Edoxaban गंभीर
- Acetylsalicylic acid + Edoxaban गंभीर
- Argatroban + Edoxaban गंभीर
- Aspirin rectal + Edoxaban गंभीर
Defibrotide के अन्य इंटरैक्शन
- Alteplase + Defibrotide निषिद्ध
- Apixaban + Defibrotide निषिद्ध
- Argatroban + Defibrotide निषिद्ध
- Dabigatran etexilate + Defibrotide निषिद्ध
- Dalteparin + Defibrotide निषिद्ध
- Defibrotide + Enoxaparin निषिद्ध
अक्सर पूछे जाने वाले प्रश्न
Can I take Defibrotide with Edoxaban?
MediHelp rates the interaction as contraindicated. Defibrotide and Edoxaban are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Defibrotide has profibrinolytic and antithrombotic activity and may add to the bleeding risk of anticoagulants such as edoxaban. Defibrotide labeling contraindicates concomitant systemic anticoagulants or fibrinolytics. Serious hemorrhage is the concern.
How serious is the interaction between Defibrotide and Edoxaban?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer; hold edoxaban while defibrotide is being given. Resume anticoagulation only after defibrotide therapy is finished and bleeding risk has been reassessed.
What other medicines interact with Edoxaban?
MediHelp also lists interactions of Edoxaban with, for example, Apixaban, Ketorolac, Abciximab. The full list is on the Edoxaban page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
