दवाओं की अंतःक्रिया
Dexamethasone-neomycin-polymyxin + Mifepristone
गंभीरता: गंभीर
Dexamethasone-neomycin-polymyxin and Mifepristone: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Mifepristone is a glucocorticoid receptor antagonist and CYP3A4 inhibitor, so it can reduce dexamethasone effect at the receptor while raising its levels. Mifepristone's label advises that corticosteroid treatment may be less effective. This is most relevant for systemic dexamethasone.
इस इंटरैक्शन का सरल भाषा में अर्थ
Dexamethasone-neomycin-polymyxin and Mifepristone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Dexamethasone-neomycin-polymyxin belongs to Anti Bacterial; Mifepristone belongs to Endocrine.
ऐसा क्यों होता है
Glucocorticoid receptor antagonism by mifepristone plus CYP3A4 inhibition of dexamethasone metabolism.
क्या करें
With systemic dexamethasone, anticipate reduced response and higher steroid doses may be needed, with close monitoring. Avoid relying on corticosteroids in patients on chronic mifepristone, such as for Cushing syndrome.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Dexamethasone-neomycin-polymyxin और Mifepristone की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Dexamethasone-neomycin-polymyxin के अन्य इंटरैक्शन
- Dexamethasone-neomycin-polymyxin + Ketorolac गंभीर
- Dexamethasone-neomycin-polymyxin + Lapatinib गंभीर
- Dexamethasone-neomycin-polymyxin + Levofloxacin गंभीर
- Dexamethasone-neomycin-polymyxin + Moxifloxacin गंभीर
- Aldesleukin + Dexamethasone-neomycin-polymyxin मध्यम
- Allogeneic cultured keratinocytes / fibroblasts in bovine collagen + Dexamethasone-neomycin-polymyxin मध्यम
Mifepristone के अन्य इंटरैक्शन
- Apixaban + Mifepristone निषिद्ध
- Argatroban + Mifepristone निषिद्ध
- Cisapride + Mifepristone निषिद्ध
- Cortisone + Mifepristone निषिद्ध
- Cyclosporin + Mifepristone निषिद्ध
- Dabigatran etexilate + Mifepristone निषिद्ध
अक्सर पूछे जाने वाले प्रश्न
Can I take Dexamethasone-neomycin-polymyxin with Mifepristone?
MediHelp rates the interaction as major. Dexamethasone-neomycin-polymyxin and Mifepristone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Mifepristone is a glucocorticoid receptor antagonist and CYP3A4 inhibitor, so it can reduce dexamethasone effect at the receptor while raising its levels. Mifepristone's label advises that corticosteroid treatment may be less effective. This is most relevant for systemic dexamethasone.
How serious is the interaction between Dexamethasone-neomycin-polymyxin and Mifepristone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: With systemic dexamethasone, anticipate reduced response and higher steroid doses may be needed, with close monitoring. Avoid relying on corticosteroids in patients on chronic mifepristone, such as for Cushing syndrome.
What other medicines interact with Dexamethasone-neomycin-polymyxin?
MediHelp also lists interactions of Dexamethasone-neomycin-polymyxin with, for example, Ketorolac, Lapatinib, Levofloxacin. The full list is on the Dexamethasone-neomycin-polymyxin page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
