दवाओं की अंतःक्रिया
Dienogest / estradiol valerate + Griseofulvin
गंभीरता: गंभीर
Dienogest / estradiol valerate and Griseofulvin: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Griseofulvin may lower estradiol and dienogest concentrations through enzyme induction, and it has been associated with contraceptive failure and breakthrough bleeding. Reduced hormone exposure may compromise contraceptive reliability.
इस इंटरैक्शन का सरल भाषा में अर्थ
Dienogest / estradiol valerate and Griseofulvin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
ऐसा क्यों होता है
Induction of CYP3A4 by griseofulvin increases metabolism of estradiol and dienogest.
क्या करें
Advise an additional non-hormonal contraceptive method during griseofulvin treatment and for about 28 days after stopping it.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Dienogest / estradiol valerate और Griseofulvin की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 7 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Griseofulvin के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Dienogest / estradiol valerate with Griseofulvin?
MediHelp rates the interaction as major. Dienogest / estradiol valerate and Griseofulvin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Griseofulvin may lower estradiol and dienogest concentrations through enzyme induction, and it has been associated with contraceptive failure and breakthrough bleeding. Reduced hormone exposure may compromise contraceptive reliability.
How serious is the interaction between Dienogest / estradiol valerate and Griseofulvin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise an additional non-hormonal contraceptive method during griseofulvin treatment and for about 28 days after stopping it.
What other medicines interact with Griseofulvin?
MediHelp also lists interactions of Griseofulvin with, for example, Cyclosporine, Cyclosporin, Desogestrel-ethinyl estradiol. The full list is on the Griseofulvin page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
