सामग्री पर जाएँ

दवाओं की अंतःक्रिया

Dofetilide + Quinidine

गंभीरता: निषिद्ध

Dofetilide and Quinidine: contraindicated interaction.

अंतिम अपडेट

केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।

इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।

सारांश

Both drugs prolong cardiac repolarization, and concurrent use raises the risk of torsades de pointes and sudden death. Quinidine may also reduce renal clearance of dofetilide, increasing its exposure.

इस इंटरैक्शन का सरल भाषा में अर्थ

Dofetilide and Quinidine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Dofetilide belongs to Cardiovascular; Quinidine belongs to Anti Parasitic.

साक्ष्य स्तर: Moderate

ऐसा क्यों होता है

Additive potassium channel blockade causing QT prolongation, with possible reduced renal elimination of dofetilide.

क्या करें

Do not coadminister; allow adequate washout of the first antiarrhythmic before starting the other, under ECG monitoring.

फार्मासिस्ट से क्या पूछें

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ सदस्यों के लिए

पूरा पेज खोलें

Dofetilide और Quinidine की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।

अक्सर पूछे जाने वाले प्रश्न

Can I take Dofetilide with Quinidine?

MediHelp rates the interaction as contraindicated. Dofetilide and Quinidine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs prolong cardiac repolarization, and concurrent use raises the risk of torsades de pointes and sudden death. Quinidine may also reduce renal clearance of dofetilide, increasing its exposure.

How serious is the interaction between Dofetilide and Quinidine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not coadminister; allow adequate washout of the first antiarrhythmic before starting the other, under ECG monitoring.

What other medicines interact with Quinidine?

MediHelp also lists interactions of Quinidine with, for example, Adagrasib, Arsenic trioxide, Artemether / lumefantrine. The full list is on the Quinidine page.

MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर

MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।

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