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दवाओं की अंतःक्रिया

Duloxetine + Rasagiline

गंभीरता: निषिद्ध

Duloxetine and Rasagiline: contraindicated interaction.

अंतिम अपडेट

केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।

इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।

सारांश

Combining an MAO inhibitor with an SNRI can cause serotonin syndrome and severe CNS toxicity with hyperthermia. Duloxetine labeling contraindicates use with MAO inhibitors, and rasagiline labeling advises against combining with antidepressants.

इस इंटरैक्शन का सरल भाषा में अर्थ

Duloxetine and Rasagiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Duloxetine belongs to Central Nervous System; Rasagiline belongs to Central Nervous System.

साक्ष्य स्तर: High

ऐसा क्यों होता है

MAO-B inhibition (with reduced selectivity at higher doses) combined with serotonin and norepinephrine reuptake inhibition causes excess synaptic monoamines.

क्या करें

Do not coadminister. Allow at least 14 days after stopping rasagiline before starting duloxetine, and at least 5 days after stopping duloxetine before starting rasagiline.

फार्मासिस्ट से क्या पूछें

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ सदस्यों के लिए

पूरा पेज खोलें

Duloxetine और Rasagiline की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।

अक्सर पूछे जाने वाले प्रश्न

Can I take Duloxetine with Rasagiline?

MediHelp rates the interaction as contraindicated. Duloxetine and Rasagiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Combining an MAO inhibitor with an SNRI can cause serotonin syndrome and severe CNS toxicity with hyperthermia. Duloxetine labeling contraindicates use with MAO inhibitors, and rasagiline labeling advises against combining with antidepressants.

How serious is the interaction between Duloxetine and Rasagiline?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not coadminister. Allow at least 14 days after stopping rasagiline before starting duloxetine, and at least 5 days after stopping duloxetine before starting rasagiline.

What other medicines interact with Duloxetine?

MediHelp also lists interactions of Duloxetine with, for example, Isocarboxazid, Linezolid, Methylene blue. The full list is on the Duloxetine page.

MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर

MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।

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