दवाओं की अंतःक्रिया
Elivaldogene autotemcel + Stavudine
गंभीरता: गंभीर
Elivaldogene autotemcel and Stavudine: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Antiretrovirals can inhibit lentiviral vector transduction of the patient's collected stem cells, which may compromise manufacture and engraftment of the gene therapy product. Antiretrovirals must therefore be stopped before stem cell mobilization and apheresis.
इस इंटरैक्शन का सरल भाषा में अर्थ
Elivaldogene autotemcel and Stavudine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
ऐसा क्यों होता है
Antiretroviral reverse transcriptase inhibitors can interfere with lentiviral vector transduction during manufacturing of the gene-modified cells.
क्या करें
Stop stavudine at least 1 month before mobilization and keep it off until all apheresis cycles are completed. Plan alternative HIV management with the infectious disease team.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Elivaldogene autotemcel और Stavudine की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Stavudine के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Elivaldogene autotemcel with Stavudine?
MediHelp rates the interaction as major. Elivaldogene autotemcel and Stavudine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Antiretrovirals can inhibit lentiviral vector transduction of the patient's collected stem cells, which may compromise manufacture and engraftment of the gene therapy product. Antiretrovirals must therefore be stopped before stem cell mobilization and apheresis.
How serious is the interaction between Elivaldogene autotemcel and Stavudine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Stop stavudine at least 1 month before mobilization and keep it off until all apheresis cycles are completed. Plan alternative HIV management with the infectious disease team.
What other medicines interact with Stavudine?
MediHelp also lists interactions of Stavudine with, for example, Didanosine, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Hydroxycarbamide. The full list is on the Stavudine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
