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Enalapril-hydrochlorothiazide + Ethacrynic acid

गंभीरता: गंभीर

Enalapril-hydrochlorothiazide and Ethacrynic acid: major interaction.

अंतिम अपडेट

केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।

इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।

सारांश

Ethacrynic acid is a potent loop diuretic that adds to the thiazide's sodium, water and potassium losses. With enalapril, the resulting volume depletion can cause marked hypotension and acute kidney injury, plus hypokalemia and hypomagnesemia.

इस इंटरैक्शन का सरल भाषा में अर्थ

Enalapril-hydrochlorothiazide and Ethacrynic acid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Enalapril-hydrochlorothiazide belongs to Cardiovascular; Ethacrynic acid belongs to Cardiovascular.

साक्ष्य स्तर: High

ऐसा क्यों होता है

Sequential nephron blockade with additive diuresis and electrolyte loss, combined with ACE inhibitor reduction of angiotensin II-dependent glomerular perfusion.

क्या करें

Start with low doses and monitor blood pressure, renal function and electrolytes closely, especially in volume-depleted patients. Consider temporarily reducing diuretic doses when starting the combination.

फार्मासिस्ट से क्या पूछें

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ सदस्यों के लिए

पूरा पेज खोलें

Enalapril-hydrochlorothiazide और Ethacrynic acid की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

वेब पर Pro+ को 7 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।

अक्सर पूछे जाने वाले प्रश्न

Can I take Enalapril-hydrochlorothiazide with Ethacrynic acid?

MediHelp rates the interaction as major. Enalapril-hydrochlorothiazide and Ethacrynic acid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ethacrynic acid is a potent loop diuretic that adds to the thiazide's sodium, water and potassium losses. With enalapril, the resulting volume depletion can cause marked hypotension and acute kidney injury, plus hypokalemia and hypomagnesemia.

How serious is the interaction between Enalapril-hydrochlorothiazide and Ethacrynic acid?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Start with low doses and monitor blood pressure, renal function and electrolytes closely, especially in volume-depleted patients. Consider temporarily reducing diuretic doses when starting the combination.

What other medicines interact with Enalapril-hydrochlorothiazide?

MediHelp also lists interactions of Enalapril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Protein a column. The full list is on the Enalapril-hydrochlorothiazide page.

MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर

MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।

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