दवाओं की अंतःक्रिया
Captopril-hydrochlorothiazide + Ethacrynic acid
गंभीरता: गंभीर
Captopril-hydrochlorothiazide and Ethacrynic acid: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Ethacrynic acid is a potent loop diuretic that, with hydrochlorothiazide, produces sequential nephron blockade with marked diuresis and loss of potassium, sodium and magnesium. Together with an ACE inhibitor this may cause severe hypotension and acute kidney injury, particularly in volume-depleted patients.
इस इंटरैक्शन का सरल भाषा में अर्थ
Captopril-hydrochlorothiazide and Ethacrynic acid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Captopril-hydrochlorothiazide belongs to Cardiovascular; Ethacrynic acid belongs to Cardiovascular.
ऐसा क्यों होता है
Additive natriuresis and electrolyte wasting from loop and thiazide diuretics, plus ACE inhibitor reduction of glomerular filtration pressure in volume depletion.
क्या करें
Monitor blood pressure, volume status, electrolytes and creatinine closely, particularly in the first days. Reduce or hold the diuretics if hypotension, hypokalemia or rising creatinine occurs.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Captopril-hydrochlorothiazide और Ethacrynic acid की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Captopril-hydrochlorothiazide के अन्य इंटरैक्शन
- Aliskiren + Captopril-hydrochlorothiazide निषिद्ध
- Captopril-hydrochlorothiazide + Dofetilide निषिद्ध
- Captopril-hydrochlorothiazide + Sacubitril / valsartan निषिद्ध
- Aceclofenac + Captopril-hydrochlorothiazide गंभीर
- Aldesleukin + Captopril-hydrochlorothiazide गंभीर
- Amifostine + Captopril-hydrochlorothiazide गंभीर
Ethacrynic acid के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Captopril-hydrochlorothiazide with Ethacrynic acid?
MediHelp rates the interaction as major. Captopril-hydrochlorothiazide and Ethacrynic acid can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ethacrynic acid is a potent loop diuretic that, with hydrochlorothiazide, produces sequential nephron blockade with marked diuresis and loss of potassium, sodium and magnesium. Together with an ACE inhibitor this may cause severe hypotension and acute kidney injury, particularly in volume-depleted patients.
How serious is the interaction between Captopril-hydrochlorothiazide and Ethacrynic acid?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, volume status, electrolytes and creatinine closely, particularly in the first days. Reduce or hold the diuretics if hypotension, hypokalemia or rising creatinine occurs.
What other medicines interact with Captopril-hydrochlorothiazide?
MediHelp also lists interactions of Captopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sacubitril / valsartan. The full list is on the Captopril-hydrochlorothiazide page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
