दवाओं की अंतःक्रिया
Fezolinetant + Fluvoxamine
गंभीरता: निषिद्ध
Fezolinetant and Fluvoxamine: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Fezolinetant is metabolised mainly by CYP1A2, and fluvoxamine is a strong CYP1A2 inhibitor that greatly increases its exposure. This raises the risk of adverse effects including hepatotoxicity.
इस इंटरैक्शन का सरल भाषा में अर्थ
Fezolinetant and Fluvoxamine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Fezolinetant belongs to Endocrine; Fluvoxamine belongs to Central Nervous System.
ऐसा क्यों होता है
Strong CYP1A2 inhibition by fluvoxamine markedly reduces fezolinetant clearance.
क्या करें
Do not use together; choose a different antidepressant or vasomotor symptom treatment. If fezolinetant is used, monitor liver tests per labeling.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Fezolinetant और Fluvoxamine की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Fluvoxamine के अन्य इंटरैक्शन
- Agomelatine + Fluvoxamine निषिद्ध
- Alosetron + Fluvoxamine निषिद्ध
- Fluvoxamine + Isocarboxazid निषिद्ध
- Fluvoxamine + Mavacamten निषिद्ध
- Fluvoxamine + Methylene blue निषिद्ध
- Fluvoxamine + Phenelzine निषिद्ध
Fezolinetant के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Fezolinetant with Fluvoxamine?
MediHelp rates the interaction as contraindicated. Fezolinetant and Fluvoxamine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Fezolinetant is metabolised mainly by CYP1A2, and fluvoxamine is a strong CYP1A2 inhibitor that greatly increases its exposure. This raises the risk of adverse effects including hepatotoxicity.
How serious is the interaction between Fezolinetant and Fluvoxamine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; choose a different antidepressant or vasomotor symptom treatment. If fezolinetant is used, monitor liver tests per labeling.
What other medicines interact with Fluvoxamine?
MediHelp also lists interactions of Fluvoxamine with, for example, Agomelatine, Alosetron, Isocarboxazid. The full list is on the Fluvoxamine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
