दवाओं की अंतःक्रिया
Folic acid + Glucarpidase
गंभीरता: मध्यम
Folic acid and Glucarpidase: moderate interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Glucarpidase hydrolyzes folates and antifolates such as methotrexate, and can degrade folic acid and related folate compounds like leucovorin. Folate rescue given around glucarpidase may therefore be less effective.
इस इंटरैक्शन का सरल भाषा में अर्थ
Folic acid and Glucarpidase can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Folic acid belongs to Miscellaneous; Glucarpidase belongs to Miscellaneous.
ऐसा क्यों होता है
Glucarpidase is a carboxypeptidase that cleaves the terminal glutamate residue from folates, inactivating them.
क्या करें
Do not give leucovorin within 2 hours before or after glucarpidase, since it is a substrate, and continue folate rescue as directed by the protocol afterward.
फार्मासिस्ट से क्या पूछें
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Folic acid और Glucarpidase की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 7 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Folic acid के अन्य इंटरैक्शन
Glucarpidase के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Folic acid with Glucarpidase?
MediHelp rates the interaction as moderate. Folic acid and Glucarpidase can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Glucarpidase hydrolyzes folates and antifolates such as methotrexate, and can degrade folic acid and related folate compounds like leucovorin. Folate rescue given around glucarpidase may therefore be less effective.
How serious is the interaction between Folic acid and Glucarpidase?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give leucovorin within 2 hours before or after glucarpidase, since it is a substrate, and continue folate rescue as directed by the protocol afterward.
What other medicines interact with Folic acid?
MediHelp also lists interactions of Folic acid with, for example, Ethotoin, Fosphenytoin, Methotrexate. The full list is on the Folic acid page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
