दवाओं की अंतःक्रिया
Glyceryl trinitrate pr + Sildenafil
गंभीरता: निषिद्ध
Glyceryl trinitrate pr and Sildenafil: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Sildenafil markedly potentiates the hypotensive effect of nitrates, including rectal glyceryl trinitrate. Profound and potentially fatal hypotension, syncope or myocardial ischemia can occur.
इस इंटरैक्शन का सरल भाषा में अर्थ
Glyceryl trinitrate pr and Sildenafil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
ऐसा क्यों होता है
Nitrates raise cGMP via nitric oxide and sildenafil blocks its breakdown by PDE5, causing exaggerated vasodilation.
क्या करें
Do not combine. If a nitrate is needed after sildenafil, withhold it for at least 24 hours and give only under medical supervision.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Glyceryl trinitrate pr और Sildenafil की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Sildenafil के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Glyceryl trinitrate pr with Sildenafil?
MediHelp rates the interaction as contraindicated. Glyceryl trinitrate pr and Sildenafil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Sildenafil markedly potentiates the hypotensive effect of nitrates, including rectal glyceryl trinitrate. Profound and potentially fatal hypotension, syncope or myocardial ischemia can occur.
How serious is the interaction between Glyceryl trinitrate pr and Sildenafil?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine. If a nitrate is needed after sildenafil, withhold it for at least 24 hours and give only under medical supervision.
What other medicines interact with Sildenafil?
MediHelp also lists interactions of Sildenafil with, for example, Amyl nitrite, Atazanavir, Cobicistat. The full list is on the Sildenafil page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
