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दवाओं की अंतःक्रिया

Hydrocodone + Isocarboxazid

गंभीरता: निषिद्ध

Hydrocodone and Isocarboxazid: contraindicated interaction.

अंतिम अपडेट

केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।

इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।

सारांश

MAO inhibitors given with opioids can cause serotonin syndrome or unpredictable opioid toxicity, including respiratory depression and coma. The risk persists for about two weeks after the MAOI is stopped.

इस इंटरैक्शन का सरल भाषा में अर्थ

Hydrocodone and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Hydrocodone belongs to Musculoskeletal; Isocarboxazid belongs to Central Nervous System.

साक्ष्य स्तर: Moderate

ऐसा क्यों होता है

Nonselective MAO inhibition raises serotonergic and noradrenergic activity and may alter opioid effects, causing serotonin toxicity or CNS depression.

क्या करें

Do not use hydrocodone during or within 14 days of an MAOI; choose a non-opioid or non-interacting analgesic. If an opioid is unavoidable, use closely monitored small test doses.

फार्मासिस्ट से क्या पूछें

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ सदस्यों के लिए

पूरा पेज खोलें

Hydrocodone और Isocarboxazid की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।

अक्सर पूछे जाने वाले प्रश्न

Can I take Hydrocodone with Isocarboxazid?

MediHelp rates the interaction as contraindicated. Hydrocodone and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. MAO inhibitors given with opioids can cause serotonin syndrome or unpredictable opioid toxicity, including respiratory depression and coma. The risk persists for about two weeks after the MAOI is stopped.

How serious is the interaction between Hydrocodone and Isocarboxazid?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use hydrocodone during or within 14 days of an MAOI; choose a non-opioid or non-interacting analgesic. If an opioid is unavoidable, use closely monitored small test doses.

What other medicines interact with Hydrocodone?

MediHelp also lists interactions of Hydrocodone with, for example, Alvimopan, Bupropion-naltrexone, Olanzapine / samidorphan. The full list is on the Hydrocodone page.

MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर

MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।

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