दवाओं की अंतःक्रिया
Hydromorphone + Isocarboxazid
गंभीरता: निषिद्ध
Hydromorphone and Isocarboxazid: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Opioids combined with nonselective MAOIs have caused serious reactions including hypotension, hyperthermia, agitation, coma and respiratory depression. Hydromorphone labeling advises against use with MAOIs or within 14 days of stopping them.
इस इंटरैक्शन का सरल भाषा में अर्थ
Hydromorphone and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Hydromorphone belongs to Musculoskeletal; Isocarboxazid belongs to Central Nervous System.
ऐसा क्यों होता है
Irreversible MAO inhibition may potentiate opioid CNS and respiratory depression and cause serotonergic or autonomic instability; the exact mechanism is not fully defined.
क्या करें
Do not use together and allow at least 14 days after stopping the MAOI before starting hydromorphone. Use a non-serotonergic alternative analgesic if needed.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Hydromorphone और Isocarboxazid की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Hydromorphone के अन्य इंटरैक्शन
- Alvimopan + Hydromorphone निषिद्ध
- Bupropion-naltrexone + Hydromorphone निषिद्ध
- Hydromorphone + Olanzapine / samidorphan निषिद्ध
- Hydromorphone + Phenelzine निषिद्ध
- Hydromorphone + Tranylcypromine निषिद्ध
- Alfentanil + Hydromorphone गंभीर
Isocarboxazid के अन्य इंटरैक्शन
- 5-HTP + Isocarboxazid निषिद्ध
- Amitriptyline + Isocarboxazid निषिद्ध
- Amobarbital + Isocarboxazid निषिद्ध
- Amoxapine + Isocarboxazid निषिद्ध
- Apraclonidine + Isocarboxazid निषिद्ध
- Atomoxetine + Isocarboxazid निषिद्ध
अक्सर पूछे जाने वाले प्रश्न
Can I take Hydromorphone with Isocarboxazid?
MediHelp rates the interaction as contraindicated. Hydromorphone and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Opioids combined with nonselective MAOIs have caused serious reactions including hypotension, hyperthermia, agitation, coma and respiratory depression. Hydromorphone labeling advises against use with MAOIs or within 14 days of stopping them.
How serious is the interaction between Hydromorphone and Isocarboxazid?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together and allow at least 14 days after stopping the MAOI before starting hydromorphone. Use a non-serotonergic alternative analgesic if needed.
What other medicines interact with Hydromorphone?
MediHelp also lists interactions of Hydromorphone with, for example, Alvimopan, Bupropion-naltrexone, Olanzapine / samidorphan. The full list is on the Hydromorphone page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
