दवाओं की अंतःक्रिया
Irinotecan + Trastuzumab deruxtecan
गंभीरता: गंभीर
Irinotecan and Trastuzumab deruxtecan: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Trastuzumab deruxtecan carries a topoisomerase I inhibitor payload and causes neutropenia, while irinotecan is also myelosuppressive. Combined use may add hematologic toxicity, diarrhea and infection risk.
इस इंटरैक्शन का सरल भाषा में अर्थ
Irinotecan and Trastuzumab deruxtecan can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Irinotecan belongs to Oncology; Trastuzumab deruxtecan belongs to Oncology.
ऐसा क्यों होता है
Additive myelosuppression and gastrointestinal toxicity from two topoisomerase I inhibitor exposures.
क्या करें
Avoid routine concurrent use; if combined, monitor complete blood counts frequently and reduce doses or delay treatment for neutropenia.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Irinotecan और Trastuzumab deruxtecan की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Irinotecan के अन्य इंटरैक्शन
Trastuzumab deruxtecan के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Irinotecan with Trastuzumab deruxtecan?
MediHelp rates the interaction as major. Irinotecan and Trastuzumab deruxtecan can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Trastuzumab deruxtecan carries a topoisomerase I inhibitor payload and causes neutropenia, while irinotecan is also myelosuppressive. Combined use may add hematologic toxicity, diarrhea and infection risk.
How serious is the interaction between Irinotecan and Trastuzumab deruxtecan?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid routine concurrent use; if combined, monitor complete blood counts frequently and reduce doses or delay treatment for neutropenia.
What other medicines interact with Irinotecan?
MediHelp also lists interactions of Irinotecan with, for example, Clozapine, Sacituzumab govitecan, Adenovirus types 4 and 7 live. The full list is on the Irinotecan page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
