दवाओं की अंतःक्रिया
Ivacaftor + Oxcarbazepine
गंभीरता: गंभीर
Ivacaftor and Oxcarbazepine: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Oxcarbazepine may reduce ivacaftor exposure via CYP3A4 induction. Strong inducers lower ivacaftor exposure substantially, and oxcarbazepine is a weaker inducer with uncertain but possible effects. Loss of CFTR modulator efficacy is possible.
इस इंटरैक्शन का सरल भाषा में अर्थ
Ivacaftor and Oxcarbazepine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Ivacaftor belongs to Miscellaneous; Oxcarbazepine belongs to Central Nervous System.
ऐसा क्यों होता है
Oxcarbazepine induces CYP3A4, increasing ivacaftor metabolism.
क्या करें
Prefer a non-inducing anticonvulsant. If it is used, monitor lung function and clinical response to ivacaftor.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Ivacaftor और Oxcarbazepine की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Oxcarbazepine के अन्य इंटरैक्शन
Ivacaftor के अन्य इंटरैक्शन
- Ensitrelvir + Ivacaftor निषिद्ध
- Apalutamide + Ivacaftor गंभीर
- Carbamazepine + Ivacaftor गंभीर
- Clarithromycin + Ivacaftor गंभीर
- Efavirenz + Ivacaftor गंभीर
- Enzalutamide + Ivacaftor गंभीर
अक्सर पूछे जाने वाले प्रश्न
Can I take Ivacaftor with Oxcarbazepine?
MediHelp rates the interaction as major. Ivacaftor and Oxcarbazepine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oxcarbazepine may reduce ivacaftor exposure via CYP3A4 induction. Strong inducers lower ivacaftor exposure substantially, and oxcarbazepine is a weaker inducer with uncertain but possible effects. Loss of CFTR modulator efficacy is possible.
How serious is the interaction between Ivacaftor and Oxcarbazepine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Prefer a non-inducing anticonvulsant. If it is used, monitor lung function and clinical response to ivacaftor.
What other medicines interact with Oxcarbazepine?
MediHelp also lists interactions of Oxcarbazepine with, for example, Cabotegravir, Rilpivirine, Artemether / lumefantrine. The full list is on the Oxcarbazepine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
