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दवाओं की अंतःक्रिया

Levodopa + Tranylcypromine

गंभीरता: निषिद्ध

Levodopa and Tranylcypromine: contraindicated interaction.

अंतिम अपडेट

केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।

इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।

सारांश

Levodopa is converted to dopamine and norepinephrine, and nonselective MAO inhibition prevents their breakdown. This can produce hypertensive crisis with severe headache and cardiovascular events.

इस इंटरैक्शन का सरल भाषा में अर्थ

Levodopa and Tranylcypromine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Levodopa belongs to Central Nervous System; Tranylcypromine belongs to Central Nervous System.

साक्ष्य स्तर: High

ऐसा क्यों होता है

Increased catecholamine formation with blocked MAO-A and MAO-B degradation causes exaggerated pressor effects.

क्या करें

Avoid the combination and stop the nonselective MAOI at least 14 days before starting levodopa. Selective MAO-B inhibitors are used in Parkinson disease under guidance.

फार्मासिस्ट से क्या पूछें

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ सदस्यों के लिए

पूरा पेज खोलें

Levodopa और Tranylcypromine की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

वेब पर Pro+ को 7 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।

अक्सर पूछे जाने वाले प्रश्न

Can I take Levodopa with Tranylcypromine?

MediHelp rates the interaction as contraindicated. Levodopa and Tranylcypromine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Levodopa is converted to dopamine and norepinephrine, and nonselective MAO inhibition prevents their breakdown. This can produce hypertensive crisis with severe headache and cardiovascular events.

How serious is the interaction between Levodopa and Tranylcypromine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and stop the nonselective MAOI at least 14 days before starting levodopa. Selective MAO-B inhibitors are used in Parkinson disease under guidance.

What other medicines interact with Tranylcypromine?

MediHelp also lists interactions of Tranylcypromine with, for example, 5-HTP, Amitriptyline, Amoxapine. The full list is on the Tranylcypromine page.

MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर

MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।

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