दवाओं की अंतःक्रिया
Levodopa + Phenelzine (nonselective MAOI)
गंभीरता: निषिद्ध
Levodopa and Phenelzine (nonselective MAOI): contraindicated interaction.
अंतिम अपडेट स्रोत: US FDA label
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Levodopa with a nonselective MAOI such as phenelzine can cause hypertensive crisis because peripheral dopamine and norepinephrine accumulate. Levodopa labeling contraindicates nonselective MAOIs, which must be stopped at least two weeks beforehand. Severe headache, palpitations and dangerously high blood pressure may occur.
इस इंटरैक्शन का सरल भाषा में अर्थ
Levodopa and Phenelzine (nonselective MAOI) are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
ऐसा क्यों होता है
Nonselective MAO inhibition blocks breakdown of dopamine and norepinephrine formed from levodopa, causing excessive catecholamine accumulation and a pressor response.
क्या करें
Do not combine. Stop phenelzine at least 14 days before starting levodopa.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Levodopa और Phenelzine (nonselective MAOI) की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 7 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
संदर्भ
Levodopa के अन्य इंटरैक्शन
- Isocarboxazid + Levodopa निषिद्ध
- Levodopa + Phenelzine निषिद्ध
- Levodopa + Procarbazine निषिद्ध
- Levodopa + Tranylcypromine निषिद्ध
- Amisulpride + Levodopa गंभीर
- Chlorpromazine + Levodopa गंभीर
अक्सर पूछे जाने वाले प्रश्न
Can I take Levodopa with Phenelzine (nonselective MAOI)?
MediHelp rates the interaction as contraindicated. Levodopa and Phenelzine (nonselective MAOI) are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Levodopa with a nonselective MAOI such as phenelzine can cause hypertensive crisis because peripheral dopamine and norepinephrine accumulate. Levodopa labeling contraindicates nonselective MAOIs, which must be stopped at least two weeks beforehand. Severe headache, palpitations and dangerously high blood pressure may occur.
How serious is the interaction between Levodopa and Phenelzine (nonselective MAOI)?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine. Stop phenelzine at least 14 days before starting levodopa.
What other medicines interact with Levodopa?
MediHelp also lists interactions of Levodopa with, for example, Isocarboxazid, Phenelzine, Procarbazine. The full list is on the Levodopa page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
