दवाओं की अंतःक्रिया
Methylene blue + Nortriptyline
गंभीरता: निषिद्ध
Methylene blue and Nortriptyline: contraindicated interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Methylene blue inhibits MAO-A, and combining it with serotonergic drugs such as nortriptyline can cause serotonin syndrome, which may be severe. The FDA has issued a warning on this interaction.
इस इंटरैक्शन का सरल भाषा में अर्थ
Methylene blue and Nortriptyline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
ऐसा क्यों होता है
MAO-A inhibition by methylene blue added to serotonin reuptake inhibition by nortriptyline.
क्या करें
Avoid the combination in non-emergency settings. If methylene blue is urgent, stop the serotonergic drug and monitor for CNS toxicity for up to two weeks or 24 hours after the last methylene blue dose, whichever comes first.
फार्मासिस्ट से क्या पूछें
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Methylene blue और Nortriptyline की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Nortriptyline के अन्य इंटरैक्शन
- Disopyramide + Nortriptyline निषिद्ध
- Dofetilide + Nortriptyline निषिद्ध
- Dronedarone + Nortriptyline निषिद्ध
- Ibutilide + Nortriptyline निषिद्ध
- Isocarboxazid + Nortriptyline निषिद्ध
- Nortriptyline + Pentamidine निषिद्ध
अक्सर पूछे जाने वाले प्रश्न
Can I take Methylene blue with Nortriptyline?
MediHelp rates the interaction as contraindicated. Methylene blue and Nortriptyline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Methylene blue inhibits MAO-A, and combining it with serotonergic drugs such as nortriptyline can cause serotonin syndrome, which may be severe. The FDA has issued a warning on this interaction.
How serious is the interaction between Methylene blue and Nortriptyline?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination in non-emergency settings. If methylene blue is urgent, stop the serotonergic drug and monitor for CNS toxicity for up to two weeks or 24 hours after the last methylene blue dose, whichever comes first.
What other medicines interact with Nortriptyline?
MediHelp also lists interactions of Nortriptyline with, for example, Disopyramide, Dofetilide, Dronedarone. The full list is on the Nortriptyline page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
