दवाओं की अंतःक्रिया
Mosapride + Prucalopride
गंभीरता: मध्यम
Mosapride and Prucalopride: moderate interaction.
अंतिम अपडेट स्रोत: US FDA label
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Both drugs are 5-HT4 receptor agonists, so using them together duplicates therapy and may increase diarrhea, abdominal cramps, nausea, and headache. This could cause dehydration and electrolyte loss, especially in older or renally impaired patients. There is no good evidence that the combination improves efficacy.
इस इंटरैक्शन का सरल भाषा में अर्थ
Mosapride and Prucalopride can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Mosapride belongs to Gastrointestinal Tract; Prucalopride belongs to Gastrointestinal Tract.
ऐसा क्यों होता है
Pharmacodynamic: additive 5-HT4 receptor agonism enhances acetylcholine release in the enteric nervous system and accelerates gastrointestinal transit. No important pharmacokinetic interaction is expected.
क्या करें
Avoid using both and choose a single prokinetic. If switching, stop one agent before starting the other.
फार्मासिस्ट से क्या पूछें
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Mosapride और Prucalopride की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
संदर्भ
- Motegrity (prucalopride) Prescribing Information — FDA Label
- Resolor (prucalopride) Summary of Product Characteristics — EMA SmPC
Mosapride के अन्य इंटरैक्शन
- Linaclotide + Mosapride मध्यम
- Lubiprostone + Mosapride मध्यम
अक्सर पूछे जाने वाले प्रश्न
Can I take Mosapride with Prucalopride?
MediHelp rates the interaction as moderate. Mosapride and Prucalopride can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs are 5-HT4 receptor agonists, so using them together duplicates therapy and may increase diarrhea, abdominal cramps, nausea, and headache. This could cause dehydration and electrolyte loss, especially in older or renally impaired patients. There is no good evidence that the combination improves efficacy.
How serious is the interaction between Mosapride and Prucalopride?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using both and choose a single prokinetic. If switching, stop one agent before starting the other.
What other medicines interact with Mosapride?
MediHelp also lists interactions of Mosapride with, for example, Linaclotide, Lubiprostone. The full list is on the Mosapride page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
