दवाओं की अंतःक्रिया
Propylthiouracil + Sodium iodide i-131
गंभीरता: गंभीर
Propylthiouracil and Sodium iodide i-131: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Antithyroid drugs reduce thyroid uptake of radioiodine, so the therapeutic radiation dose delivered to the gland may be inadequate. Treatment failure or the need for repeat dosing may result.
इस इंटरैक्शन का सरल भाषा में अर्थ
Propylthiouracil and Sodium iodide i-131 can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
ऐसा क्यों होता है
Propylthiouracil inhibits thyroid peroxidase and hormone synthesis, which lowers thyroidal radioiodine uptake and retention.
क्या करें
Stop propylthiouracil several days before I-131 administration, typically 3 to 4 days per labeling, and do not give them together. Restart afterward according to the treating specialist's plan and monitor thyroid function.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Propylthiouracil और Sodium iodide i-131 की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Propylthiouracil के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Propylthiouracil with Sodium iodide i-131?
MediHelp rates the interaction as major. Propylthiouracil and Sodium iodide i-131 can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Antithyroid drugs reduce thyroid uptake of radioiodine, so the therapeutic radiation dose delivered to the gland may be inadequate. Treatment failure or the need for repeat dosing may result.
How serious is the interaction between Propylthiouracil and Sodium iodide i-131?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Stop propylthiouracil several days before I-131 administration, typically 3 to 4 days per labeling, and do not give them together. Restart afterward according to the treating specialist's plan and monitor thyroid function.
What other medicines interact with Propylthiouracil?
MediHelp also lists interactions of Propylthiouracil with, for example, Carbamazepine, Clozapine, Methimazole. The full list is on the Propylthiouracil page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
