दवाओं की अंतःक्रिया
Pexidartinib + Propylthiouracil
गंभीरता: गंभीर
Pexidartinib and Propylthiouracil: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Both drugs can cause serious liver injury, and propylthiouracil carries a boxed warning for severe hepatotoxicity. Combining them may increase the risk of hepatic injury and complicate its attribution.
इस इंटरैक्शन का सरल भाषा में अर्थ
Pexidartinib and Propylthiouracil can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Pexidartinib belongs to Oncology; Propylthiouracil belongs to Endocrine.
ऐसा क्यों होता है
Additive hepatotoxicity from two hepatotoxic drugs.
क्या करें
Avoid the combination where possible, using methimazole for hyperthyroidism instead; if unavoidable, monitor liver enzymes and bilirubin frequently and stop at signs of liver injury.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Pexidartinib और Propylthiouracil की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Propylthiouracil के अन्य इंटरैक्शन
Pexidartinib के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Pexidartinib with Propylthiouracil?
MediHelp rates the interaction as major. Pexidartinib and Propylthiouracil can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs can cause serious liver injury, and propylthiouracil carries a boxed warning for severe hepatotoxicity. Combining them may increase the risk of hepatic injury and complicate its attribution.
How serious is the interaction between Pexidartinib and Propylthiouracil?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible, using methimazole for hyperthyroidism instead; if unavoidable, monitor liver enzymes and bilirubin frequently and stop at signs of liver injury.
What other medicines interact with Propylthiouracil?
MediHelp also lists interactions of Propylthiouracil with, for example, Carbamazepine, Clozapine, Methimazole. The full list is on the Propylthiouracil page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
