दवाओं की अंतःक्रिया
Smallpox vaccine live + Vedolizumab
गंभीरता: गंभीर
Smallpox vaccine live and Vedolizumab: major interaction.
अंतिम अपडेट स्रोत: UK SmPC
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Live vaccinia vaccine can cause progressive vaccinia and other serious complications in immunocompromised patients. Vedolizumab is gut-selective, so the risk is likely lower, but its labeling advises avoiding live vaccines unless benefit outweighs risk.
इस इंटरैक्शन का सरल भाषा में अर्थ
Smallpox vaccine live and Vedolizumab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
ऐसा क्यों होता है
Theoretical impaired immune containment of replicating vaccinia virus in a patient receiving an immunomodulating biologic.
क्या करें
Avoid live vaccinia vaccine during vedolizumab therapy unless exposure risk justifies it. If needed, weigh the benefit and monitor the vaccination site and for systemic vaccinia.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Smallpox vaccine live और Vedolizumab की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 7 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
संदर्भ
Vedolizumab के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Smallpox vaccine live with Vedolizumab?
MediHelp rates the interaction as major. Smallpox vaccine live and Vedolizumab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Live vaccinia vaccine can cause progressive vaccinia and other serious complications in immunocompromised patients. Vedolizumab is gut-selective, so the risk is likely lower, but its labeling advises avoiding live vaccines unless benefit outweighs risk.
How serious is the interaction between Smallpox vaccine live and Vedolizumab?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccinia vaccine during vedolizumab therapy unless exposure risk justifies it. If needed, weigh the benefit and monitor the vaccination site and for systemic vaccinia.
What other medicines interact with Vedolizumab?
MediHelp also lists interactions of Vedolizumab with, for example, Natalizumab, Baricitinib, Certolizumab pegol. The full list is on the Vedolizumab page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।