दवाओं की अंतःक्रिया
Golimumab + Vedolizumab
गंभीरता: गंभीर
Golimumab and Vedolizumab: major interaction.
अंतिम अपडेट स्रोत: UK SmPC
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Vedolizumab blocks gut-selective integrin-mediated lymphocyte trafficking and golimumab blocks systemic TNF-alpha. Labeling for vedolizumab advises against use with TNF blockers because of a possible increase in infection risk.
इस इंटरैक्शन का सरल भाषा में अर्थ
Golimumab and Vedolizumab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Golimumab belongs to Musculoskeletal; Vedolizumab belongs to Gastrointestinal Tract.
ऐसा क्यों होता है
Additive immunosuppression via gut-selective integrin blockade and TNF-alpha inhibition.
क्या करें
Avoid combination use. Transition from one agent to the other with a planned switch and monitor for infection.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Golimumab और Vedolizumab की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 7 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
संदर्भ
- GOBIVAZ 100 mg solution for injection in pre-filled pen - SmPC sections 4.3/4.5 (class statement: other biological therapeutics; "The combination of golimumab with other biological therapeutics used to treat the same conditions as golimumab, including anakinra and abatacept is not recommen") — electronic medicines compendium (UK SmPC)
Golimumab के अन्य इंटरैक्शन
- Bcg vaccine live + Golimumab निषिद्ध
- Etanercept + Golimumab निषिद्ध
- Golimumab + Influenza virus vaccine quadrivalent intranasal निषिद्ध
- Golimumab + Measles mumps and rubella vaccine निषिद्ध
- Golimumab + Measles mumps and rubella vaccine live निषिद्ध
- Golimumab + Measles mumps rubella and varicella vaccine live निषिद्ध
Vedolizumab के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Golimumab with Vedolizumab?
MediHelp rates the interaction as major. Golimumab and Vedolizumab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Vedolizumab blocks gut-selective integrin-mediated lymphocyte trafficking and golimumab blocks systemic TNF-alpha. Labeling for vedolizumab advises against use with TNF blockers because of a possible increase in infection risk.
How serious is the interaction between Golimumab and Vedolizumab?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combination use. Transition from one agent to the other with a planned switch and monitor for infection.
What other medicines interact with Golimumab?
MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
