Gyógyszer-kölcsönhatások
Measles mumps and rubella vaccine + Methotrexate
Súlyosság: Ellenjavallt
Measles mumps and rubella vaccine and Methotrexate: contraindicated interaction.
Utolsó frissítés
Egészségügyi szakembereknek – kizárólag referenciaként. Ez az oldal rövid összefoglaló, nem orvosi tanács, és nem helyettesíti a hivatalos alkalmazási előírást vagy a klinikai megítélést. Felírás vagy kiadás előtt mindig ellenőrizd.
Az oldal klinikai tartalma csak angol nyelven érhető el.
Összefoglaló
Methotrexate suppresses cellular and humoral immunity, so a live attenuated vaccine may produce a weaker antibody response. The vaccine viruses may also replicate unchecked, which raises the risk of disseminated vaccine-strain infection. Low-dose methotrexate carries less risk than high-dose regimens, but live vaccines remain generally avoided.
Mit jelent ez a kölcsönhatás közérthetően
Measles mumps and rubella vaccine and Methotrexate are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Measles mumps and rubella vaccine belongs to Miscellaneous; Methotrexate belongs to Oncology.
Miért jön létre
Antimetabolite-induced immunosuppression impairs the immune response to live attenuated virus and permits vaccine virus replication.
Teendő
Give live vaccines at least 4 weeks before starting methotrexate where possible, and avoid them during treatment. After stopping, wait about 3 months or until immune recovery is confirmed; specialist review is needed for low-dose cases.
Mit kérdezzen a gyógyszerészétől
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+ tagoknak
A teljes oldal feloldása
Hozz létre fiókot, és indíts Pro+ próbát, hogy elérd a(z) Measles mumps and rubella vaccine és a(z) Methotrexate teljes klinikai teendőit, a további megjegyzéseket, az evidencia részleteit és a teljes receptre szóló kölcsönhatás-ellenőrzőt.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Próbáld ki a Pro+ csomagot 14 napig ingyen a weben. Nincs szükség bankkártyára.
További kölcsönhatások – Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Ellenjavallt
- Anakinra + Measles mumps and rubella vaccine Ellenjavallt
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Ellenjavallt
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Ellenjavallt
- Azathioprine + Measles mumps and rubella vaccine Ellenjavallt
- Basiliximab + Measles mumps and rubella vaccine Ellenjavallt
További kölcsönhatások – Methotrexate
- Acitretin + Methotrexate Ellenjavallt
- Adenovirus types 4 and 7 live + Methotrexate Ellenjavallt
- Influenza virus vaccine quadrivalent intranasal + Methotrexate Ellenjavallt
- Ketorolac + Methotrexate Ellenjavallt
- Measles mumps and rubella vaccine live + Methotrexate Ellenjavallt
- Measles mumps rubella and varicella vaccine live + Methotrexate Ellenjavallt
Gyakran ismételt kérdések
Can I take Measles mumps and rubella vaccine with Methotrexate?
MediHelp rates the interaction as contraindicated. Measles mumps and rubella vaccine and Methotrexate are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Methotrexate suppresses cellular and humoral immunity, so a live attenuated vaccine may produce a weaker antibody response. The vaccine viruses may also replicate unchecked, which raises the risk of disseminated vaccine-strain infection. Low-dose methotrexate carries less risk than high-dose regimens, but live vaccines remain generally avoided.
How serious is the interaction between Measles mumps and rubella vaccine and Methotrexate?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give live vaccines at least 4 weeks before starting methotrexate where possible, and avoid them during treatment. After stopping, wait about 3 months or until immune recovery is confirmed; specialist review is needed for low-dose cases.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
Teljes monográfiák, adagolás és kölcsönhatás-ellenőrző a MediHelp alkalmazásban
Nyisd meg a teljes referenciát, ellenőrizd több gyógyszer kölcsönhatásait, és használd az adagolási eszközöket a MediHelp alkalmazásban.
