Riferimento farmaci
Atacicept
Atacicept is a medicine in the class miscellaneous. It is used for nephropathy.
- Classe del farmaco: Miscellaneous
- Indicato per: nephropathy
Ultimo aggiornamento Fonti: US FDA label
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In breve
- Classe del farmaco
- Miscellaneous
- Forme farmaceutiche comuni
- iniezione
- Dosaggi comuni
- 150 mg
- Nomi commerciali
- 1
- Paesi e mercati
- 1
Per cosa si usa
Come agisce
TACI-Fc fusion glycoprotein that binds BAFF (BLyS) and APRIL, reducing BAFF- and APRIL-mediated signaling and decreasing production of galactose-deficient IgA1 (Gd-IgA1), which is implicated in IgAN.
Dose abituale nell'adulto (sintesi del foglio illustrativo)
Primary IgA nephropathy (to reduce proteinuria): 150 mg subcutaneously once weekly
Gravidanza e allattamento
- Gravidanza
- Unknown Human data insufficient to assess risk. Based on its mechanism it may suppress immunity in the exposed infant. No malformations in mouse or rabbit studies.
- Allattamento
- Unknown No data on milk levels or infant effects. As a large protein, infant absorption is likely low. Weigh breastfeeding benefits against the mother's need.
Effetti indesiderati segnalati
- Infections
- Upper respiratory tract infection
- Local administration reactions
- Injection site reaction
- Injection site erythema
Controindicazioni
- Serious hypersensitivity to atacicept-vymj or any excipients.
Chi deve prestare attenzione
- Immunosuppression and increased risk of infections: assess for active infection before starting, monitor during treatment, and consider interruption for serious infection.
- Concomitant use with other immune-modulating drugs, including systemic corticosteroids, may increase infection risk; combined use has not been evaluated.
- May interfere with vaccine responses; complete immunizations before starting; live vaccines not recommended within 30 days before or during treatment.
Informare il farmacista o il medico di gravidanza o allattamento, malattie renali o epatiche, allergie e di ogni altro farmaco o integratore assunto.
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- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- How to give it
- Pharmacokinetics
- Patient counselling points
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Domande frequenti
What is Atacicept used for?
Atacicept is a medicine in the class miscellaneous. It is used for Nephropathy.
What side effects have been reported with Atacicept?
Infections, Upper respiratory tract infection, Local administration reactions, Injection site reaction, Injection site erythema.
Can Atacicept be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Human data insufficient to assess risk. Based on its mechanism it may suppress immunity in the exposed infant. No malformations in mouse or rabbit studies. Breastfeeding: Unknown. No data on milk levels or infant effects. As a large protein, infant absorption is likely low. Weigh breastfeeding benefits against the mother's need.
What does Atacicept interact with?
MediHelp does not list a checked interaction for Atacicept yet. Always tell your pharmacist about every medicine you take.
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