Riferimento farmaci
Clemastine
Clemastine is a medicine in the class respiratory. It is used for allergic rhinitis.
- Classe del farmaco: Respiratory
- Indicato per: allergic rhinitis
Ultimo aggiornamento
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In breve
- Classe del farmaco
- Respiratory
- Forme farmaceutiche comuni
- compressa, sciroppo, iniezione
- Dosaggi comuni
- 1 mg, 0.67 mg/5 ml, 1 mg/10 ml
- Interazioni note
- 230 (Maggiore: 19 · Moderata: 170 · Minore: 41)
- Nomi commerciali
- 6
- Paesi e mercati
- 2
Per cosa si usa
Come agisce
Clemastine competes with histamine for the histamine H1 receptor, reversible competitive inhibitor.
Dose abituale nell'adulto (sintesi del foglio illustrativo)
Allergic Rhinitis 1.34 mg PO q12hr; not to exceed 8.04 mg/day for syrup or 2.68 mg/24 hours for tablets
Gravidanza e allattamento
- Gravidanza
- Unknown Limited human data with no clear link to birth defects. Loratadine, cetirizine or chlorphenamine have more pregnancy data and are preferred.
- Allattamento
- Safe US label: do not use while nursing (antihistamines carry higher risk for infants). One 10-week-old had drowsiness, irritability, poor feeding and high-pitched crying (mother also on two antiseizure drugs). LactMed: small occasional or single bedtime doses are acceptable; prefer a non-sedating drug.
Effetti indesiderati segnalati
- Fatigue
- Sedation
- Headaches
- Dry Mouth
Controindicazioni
- Documented hypersensitivity
- Lower respiratory disease, eg, asthma (controversial)
- Preemies & neonates
Chi deve prestare attenzione
- Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely.
- Older adults may be more sensitive to the side effects of this drug, especially drowsiness, constipation, problems urinating, or confusion.
- Liquid preparations of this product may contain sugar and/or alcohol. Caution is advised if you have diabetes.
Informare il farmacista o il medico di gravidanza o allattamento, malattie renali o epatiche, allergie e di ogni altro farmaco o integratore assunto.
Interazioni principali (230)
- Alfentanil + Clemastine Major
- Benzhydrocodone / acetaminophen + Clemastine Major
- Buprenorphine buccal + Clemastine Major
- Buprenorphine long-acting + Clemastine Major
- Buprenorphine subdermal implant + Clemastine Major
- Buprenorphine transdermal + Clemastine Major
- Calcium / magnesium / potassium / sodium oxybates + Clemastine Major
- Clemastine + Dextromoramide Major
- Clemastine + Diamorphine Major
- Clemastine + Fentanyl intranasal Major
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- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Pharmacokinetics
- Patient counselling points
- Food interactions
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Altri farmaci della stessa classe
Domande frequenti
What is Clemastine used for?
Clemastine is a medicine in the class respiratory. It is used for Allergic rhinitis, Insect bites, Pruritus.
What side effects have been reported with Clemastine?
Fatigue, Sedation, Headaches, Dry Mouth.
Can Clemastine be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Limited human data with no clear link to birth defects. Loratadine, cetirizine or chlorphenamine have more pregnancy data and are preferred. Breastfeeding: Safe. US label: do not use while nursing (antihistamines carry higher risk for infants). One 10-week-old had drowsiness, irritability, poor feeding and high-pitched crying (mother also on two antiseizure drugs). LactMed: small occasional or single bedtime doses are acceptable; prefer a non-sedating drug.
What does Clemastine interact with?
MediHelp lists 230 known interactions for Clemastine. Major: 19 · Moderate: 170 · Minor: 41. The most serious include Alfentanil, Benzhydrocodone / acetaminophen, Buprenorphine buccal.
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