Riferimento farmaci
Eravacycline
Eravacycline is a medicine in the class anti bacterial. It is used for intra-abdominal infections.
- Classe del farmaco: Anti Bacterial
- Indicato per: intra-abdominal infections
Ultimo aggiornamento Fonti: US FDA label
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In breve
- Classe del farmaco
- Anti Bacterial
- Codice ATC
- J01AA13
- Forme farmaceutiche comuni
- iniezione
- Interazioni note
- 5 (Moderata: 5)
- Nomi commerciali
- 2
- Paesi e mercati
- 2
Per cosa si usa
Come agisce
Eravacycline is an antibacterial drug (tetracycline class); the label gives no further mechanism detail.
Dose abituale nell'adulto (sintesi del foglio illustrativo)
Complicated intra-abdominal infection (adults 18 years and older): 1 mg/kg IV infusion over approximately 60 minutes every 12 hours for a total of 4 to 14 days, guided by severity, location and clinical response.
Gravidanza e allattamento
- Gravidanza
- Unsafe May cause tooth discoloration and reversible inhibition of bone growth if given in the second and third trimester; limited human data. Tetracyclines can have toxic effects on the developing fetus.
- Allattamento
- Unsafe Not known if excreted in human milk; breastfeeding is not recommended during treatment and for 4 days after the last dose.
Effetti indesiderati segnalati
- Infusion site reactions
- Nausea
- Vomiting
- Diarrhea
- Hypotension
- Wound dehiscence
Controindicazioni
- Known hypersensitivity to eravacycline, tetracycline-class antibacterial drugs, or any excipients.
Chi deve prestare attenzione
- Life-threatening hypersensitivity (anaphylactic) reactions reported; avoid in patients with known tetracycline hypersensitivity and discontinue if an allergic reaction occurs.
- Use during tooth development (last half of pregnancy, infancy, childhood to age 8 years) may cause permanent tooth discoloration and enamel hypoplasia.
- Use during the second and third trimester of pregnancy, infancy and childhood up to age 8 years may cause reversible inhibition of bone growth.
Informare il farmacista o il medico di gravidanza o allattamento, malattie renali o epatiche, allergie e di ogni altro farmaco o integratore assunto.
Interazioni principali (5)
- Amoxicillin + Eravacycline Moderate
- Amoxicillin-clavulanic acid + Eravacycline Moderate
- Ampicillin + Eravacycline Moderate
- Ampicillin-sulbactam + Eravacycline Moderate
- Eravacycline + Warfarin Moderate
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- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- IV preparation and dilution
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Altri farmaci della stessa classe
Domande frequenti
What is Eravacycline used for?
Eravacycline is a medicine in the class anti bacterial. It is used for Intra-abdominal infections.
What side effects have been reported with Eravacycline?
Infusion site reactions, Nausea, Vomiting, Diarrhea, Hypotension, Wound dehiscence.
Can Eravacycline be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. May cause tooth discoloration and reversible inhibition of bone growth if given in the second and third trimester; limited human data. Tetracyclines can have toxic effects on the developing fetus. Breastfeeding: Unsafe. Not known if excreted in human milk; breastfeeding is not recommended during treatment and for 4 days after the last dose.
What does Eravacycline interact with?
MediHelp lists 5 known interactions for Eravacycline. Moderate: 5. The most serious include Amoxicillin, Amoxicillin-clavulanic acid, Ampicillin.
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