Riferimento farmaci
Itopride
Itopride is a medicine in the class gastrointestinal tract. It is used for dyspepsia.
- Classe del farmaco: Gastrointestinal Tract
- Indicato per: dyspepsia
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In breve
- Classe del farmaco
- Gastrointestinal Tract
- Forme farmaceutiche comuni
- compressa
- Dosaggi comuni
- 50 mg
- Nomi commerciali
- 16
- Paesi e mercati
- 4
Per cosa si usa
Come agisce
Itopride hydrochloride activates gastrointestinal propulsive motility due to its dopamine D2 antagonizing activity and acetylcholinesterase inhibitory activity. Itopride activates acetylcholine release and inhibits degradation.
Dose abituale nell'adulto (sintesi del foglio illustrativo)
Recommended Dose: 50 mg daily (150-mg tab taken orally 3 times a day before meals).
Gravidanza e allattamento
- Gravidanza
- Unknown Prokinetic for indigestion; not FDA-approved. Human data are lacking or limited. Irish label: use in pregnancy only if the benefits clearly outweigh the risks. Better-studied options (e.g. metoclopramide for nausea) are usually preferred.
- Allattamento
- Unknown No human data; it passes into rat milk. Irish label: decide whether to stop breastfeeding or avoid itopride; some national labels advise not breastfeeding during treatment. Domperidone or metoclopramide have more lactation data.
Effetti indesiderati segnalati
- Diarrhea
- Abdominal pain
- Gynacomastia (Rare)
- Jaundice (Rare)
Controindicazioni
- Hypersensitivity to itopride or to any of the excipients.
- Patients in whom increased gastrointestinal motility could be harmful, such as those with gastrointestinal haemorrhage, mechanical obstruction or perforation.
Chi deve prestare attenzione
- Itopride enhances the action of acetylcholine and may cause cholinergic adverse effects; use with caution.
- Do not continue treatment for a prolonged period if symptoms of functional dyspepsia do not improve; reassess the patient.
- Hepatic dysfunction and jaundice with raised AST, ALT and gamma-GT have been reported; monitor and stop treatment if abnormalities occur.
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- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Patient counselling points
- Food interactions
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Domande frequenti
What is Itopride used for?
Itopride is a medicine in the class gastrointestinal tract. It is used for Dyspepsia, Gastrointestinal dysmotility, Gastroparesis, Nausea & vomiting.
What side effects have been reported with Itopride?
Diarrhea, Abdominal pain, Gynacomastia (Rare), Jaundice (Rare).
Can Itopride be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Prokinetic for indigestion; not FDA-approved. Human data are lacking or limited. Irish label: use in pregnancy only if the benefits clearly outweigh the risks. Better-studied options (e.g. metoclopramide for nausea) are usually preferred. Breastfeeding: Unknown. No human data; it passes into rat milk. Irish label: decide whether to stop breastfeeding or avoid itopride; some national labels advise not breastfeeding during treatment. Domperidone or metoclopramide have more lactation data.
What does Itopride interact with?
MediHelp does not list a checked interaction for Itopride yet. Always tell your pharmacist about every medicine you take.
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