Riferimento farmaci
Pramoxine
Pramoxine is a medicine in the class central nervous system. It is used for burns.
- Classe del farmaco: Central Nervous System
- Indicato per: burns
Ultimo aggiornamento Fonti: US FDA label
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In breve
- Classe del farmaco
- Central Nervous System
- Forme farmaceutiche comuni
- lozione, soluzione, crema, spray, inalatore
- Dosaggi comuni
- 10 mg/ml, 1 g/100 ml, 1 g/100 g
- Nomi commerciali
- 21
- Paesi e mercati
- 1
Per cosa si usa
Come agisce
Pramoxine is a topical local anaesthetic (a morpholine ether, chemically distinct from the ester and amide anaesthetics). It stabilises the neuronal membrane by blocking voltage-gated sodium channels. This reversibly inhibits the initiation and conduction of nerve impulses in sensory nerve endings in the skin.
Dose abituale nell'adulto (sintesi del foglio illustrativo)
Pain and itching from insect bites, minor burns, sunburn, minor skin irritations, cuts, scrapes, poison ivy/oak/sumac rashes: apply to affected area, topical, not more than 3 to 4 times daily (adults and children 2 years and older)
Gravidanza e allattamento
- Gravidanza
- Safe Topical anaesthetic in anti-itch and haemorrhoid creams. Little is absorbed through the skin, so fetal exposure is expected to be minimal. Short use on small areas is acceptable; OTC labels: ask a health professional first.
- Allattamento
- Safe No milk data; skin use gives little absorption. Swallowing it mainly causes nausea and vomiting without serious toxicity (LactMed). If applied to the breast or nipple, wipe it off thoroughly before feeding.
Effetti indesiderati segnalati
- Burning at application site
- Stinging at application site
- Local skin irritation
- Redness (erythema)
- Itching or worsening of pruritus
- Skin dryness
Controindicazioni
- Do not use in the eyes or nose, or over large areas of the body for prolonged periods.
Chi deve prestare attenzione
- For external use only. Do not use in the eyes or nose, over large areas of the body, or for prolonged periods.
- Ask a doctor before use on chicken pox or measles.
- Stop use and ask a doctor if condition worsens, symptoms last more than 7 days, or clear up and occur again within a few days.
Informare il farmacista o il medico di gravidanza o allattamento, malattie renali o epatiche, allergie e di ogni altro farmaco o integratore assunto.
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- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Dosing in older adults
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- Pharmacokinetics
- Patient counselling points
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Domande frequenti
What is Pramoxine used for?
Pramoxine is a medicine in the class central nervous system. It is used for Burns, Insect bites, Pruritus.
What side effects have been reported with Pramoxine?
Burning at application site, Stinging at application site, Local skin irritation, Redness (erythema), Itching or worsening of pruritus, Skin dryness.
Can Pramoxine be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Topical anaesthetic in anti-itch and haemorrhoid creams. Little is absorbed through the skin, so fetal exposure is expected to be minimal. Short use on small areas is acceptable; OTC labels: ask a health professional first. Breastfeeding: Safe. No milk data; skin use gives little absorption. Swallowing it mainly causes nausea and vomiting without serious toxicity (LactMed). If applied to the breast or nipple, wipe it off thoroughly before feeding.
What does Pramoxine interact with?
MediHelp does not list a checked interaction for Pramoxine yet. Always tell your pharmacist about every medicine you take.
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