Riferimento farmaci
Somatropin
Somatropin is a medicine in the class endocrine. It is used for cachexia.
- Classe del farmaco: Endocrine
- Indicato per: cachexia
Ultimo aggiornamento
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In breve
- Classe del farmaco
- Endocrine
- Codice ATC
- H01AC01
- Forme farmaceutiche comuni
- iniezione, soluzione
- Dosaggi comuni
- 5 mg/1.5 ml, 10 mg/1.5 ml, 4 iu
- Interazioni note
- 122 (Moderata: 90 · Minore: 32)
- Nomi commerciali
- 40
- Paesi e mercati
- 5
Per cosa si usa
Come agisce
Purified polypeptide of recombinant human growth hormone Human growth hormone plays a role in the growth of linear bone, skeletal muscle, and organs by stimulating chondrocyte proliferation and differentiation. It also stimulates erythropoietin.
Dose abituale nell'adulto (sintesi del foglio illustrativo)
GHD (Norditropin): 0.004 mg/kg daily and may increase the dose according to individual patient requirements to up to 0.016 mg/kg daily
Gravidanza e allattamento
- Gravidanza
- Unknown Limited human data are insufficient to judge risk; decades of use have not shown a drug-related risk, and animals showed no fetal harm at about 20 times human doses. The placenta makes its own growth hormone, so treatment is often stopped in pregnancy; specialist advice.
- Allattamento
- Safe Treatment does not raise normal milk growth hormone levels, and no adverse effects have been seen in breastfed infants (US label, LactMed). Acceptable while breastfeeding. Avoid diluents with benzyl alcohol; use preservative-free saline.
Effetti indesiderati segnalati
- Edema
- Arthralgia
- Peripheral edema
- Myalgia
- Leg Edema
- Infection (non-viral)
Chi deve prestare attenzione
- When somatropin is administered SC at same site over long period of time, tissue atrophy may result; may avoid by rotating injection site
- Cases of pancreatitis reported; pediatric patients possibly at a greater risk compared to adults;
- Contraindicated in active proliferative or severe non-proliferative diabetic retinopathy
Informare il farmacista o il medico di gravidanza o allattamento, malattie renali o epatiche, allergie e di ogni altro farmaco o integratore assunto.
Interazioni principali (122)
- Acarbose + Somatropin Moderate
- Albiglutide + Somatropin Moderate
- Alogliptin + Somatropin Moderate
- Alogliptin-metformin + Somatropin Moderate
- Alogliptin-pioglitazone + Somatropin Moderate
- Betamethasone + Somatropin Moderate
- Bexagliflozin + Somatropin Moderate
- Budesonide + Somatropin Moderate
- Canagliflozin + Somatropin Moderate
- Canagliflozin-metformin + Somatropin Moderate
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- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Dosing in older adults
- Patient counselling points
- Food interactions
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Altri farmaci della stessa classe
Domande frequenti
What is Somatropin used for?
Somatropin is a medicine in the class endocrine. It is used for Cachexia, Growth hormone deficiency, Short-bowel syndrome.
What side effects have been reported with Somatropin?
Edema, Arthralgia, Peripheral edema, Myalgia, Leg Edema, Infection (non-viral).
Can Somatropin be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Limited human data are insufficient to judge risk; decades of use have not shown a drug-related risk, and animals showed no fetal harm at about 20 times human doses. The placenta makes its own growth hormone, so treatment is often stopped in pregnancy; specialist advice. Breastfeeding: Safe. Treatment does not raise normal milk growth hormone levels, and no adverse effects have been seen in breastfed infants (US label, LactMed). Acceptable while breastfeeding. Avoid diluents with benzyl alcohol; use preservative-free saline.
What does Somatropin interact with?
MediHelp lists 122 known interactions for Somatropin. Moderate: 90 · Minor: 32. The most serious include Acarbose, Albiglutide, Alogliptin.
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