Riferimento farmaci
Strontium ranelate
Strontium ranelate is a medicine in the class musculoskeletal. It is used for osteoporosis.
- Classe del farmaco: Musculoskeletal
- Indicato per: osteoporosis
Ultimo aggiornamento
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In breve
- Classe del farmaco
- Musculoskeletal
- Forme farmaceutiche comuni
- bustina
- Dosaggi comuni
- 2 g
- Interazioni note
- 10 (Maggiore: 2 · Moderata: 8)
- Nomi commerciali
- 8
- Paesi e mercati
- 2
Per cosa si usa
Come agisce
Some reports have shown that strontium ranelate can slow down the progression of osteoarthritis of the knee. This agent presents an atypical mechanism of action in which it increases deposition of new bone by osteoblasts and, simultaneously, reduces the resorption of bone by osteoclasts.
Dose abituale nell'adulto (sintesi del foglio illustrativo)
The recommended dose is one 2 g sachet once daily by oral administration.
Come si assume di solito
Simple analgesics are taken by mouth, by rectum or by infusion as needed within a daily maximum that counts every product containing the same ingredient.
Gravidanza e allattamento
- Gravidanza
- Unknown Only for osteoporosis after menopause (use now restricted; EU marketing stopped). No human data; high doses caused reversible bone effects in rat and rabbit offspring. EU label: if used inadvertently in pregnancy, stop treatment.
- Allattamento
- Unknown Not known in humans; physico-chemical data suggest strontium passes into milk. EU label: should not be used while breastfeeding. No LactMed record. Not indicated in women of breastfeeding age; use calcium and vitamin D measures instead.
Effetti indesiderati segnalati
- Headache
- Insomnia
- Hypercholesterolaemia
- Confusion
- Disturbances in consciousness
Chi deve prestare attenzione
- Contraindicated in Uncontrolled hypertension.
Paracetamol-type analgesics need care in people with liver disease, chronic alcohol use or low body weight, and the daily limit must include every combination product that contains the same ingredient.
Informare il farmacista o il medico di gravidanza o allattamento, malattie renali o epatiche, allergie e di ogni altro farmaco o integratore assunto.
Interazioni principali (10)
- Minocycline + Strontium ranelate Major
- Strontium ranelate + Tetracycline Major
- Aluminum hydroxide + Strontium ranelate Moderate
- Calcium + Strontium ranelate Moderate
- Calcium carbonate + Strontium ranelate Moderate
- Doxycycline + Strontium ranelate Moderate
- Gemifloxacin + Strontium ranelate Moderate
- Levofloxacin + Strontium ranelate Moderate
- Moxifloxacin + Strontium ranelate Moderate
- Ofloxacin + Strontium ranelate Moderate
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- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Patient counselling points
- Food interactions
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Domande frequenti
What is Strontium ranelate used for?
Strontium ranelate is a medicine in the class musculoskeletal. It is used for Osteoporosis.
What side effects have been reported with Strontium ranelate?
Headache, Insomnia, Hypercholesterolaemia, Confusion, Disturbances in consciousness.
Can Strontium ranelate be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Only for osteoporosis after menopause (use now restricted; EU marketing stopped). No human data; high doses caused reversible bone effects in rat and rabbit offspring. EU label: if used inadvertently in pregnancy, stop treatment. Breastfeeding: Unknown. Not known in humans; physico-chemical data suggest strontium passes into milk. EU label: should not be used while breastfeeding. No LactMed record. Not indicated in women of breastfeeding age; use calcium and vitamin D measures instead.
What does Strontium ranelate interact with?
MediHelp lists 10 known interactions for Strontium ranelate. Major: 2 · Moderate: 8. The most serious include Minocycline, Tetracycline, Aluminum hydroxide.
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