Interazioni tra farmaci
Acitretin + Norethindrone
Gravità: Controindicata
Acitretin and Norethindrone: contraindicated interaction.
Ultimo aggiornamento
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Sintesi
Acitretin has been reported to interfere with progestin-only contraceptives, such as minipills, reducing their effectiveness. Since acitretin is highly teratogenic, any contraceptive failure is serious. Labeling advises against progestin-only pills in this setting.
Cosa significa questa interazione in parole semplici
Acitretin and Norethindrone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Mechanism unclear; acitretin may reduce the contraceptive efficacy of low-dose progestins.
Cosa fare
Do not rely on norethindrone-only contraception during acitretin therapy. Use two reliable contraceptive methods, such as a combined hormonal method plus a barrier method, as advised by labeling.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Acitretin
- Acitretin + Demeclocycline Controindicata
- Acitretin + Doxycycline Controindicata
- Acitretin + Ethanol Controindicata
- Acitretin + Methotrexate Controindicata
- Acitretin + Minocycline Controindicata
- Acitretin + Norethisterone Controindicata
Domande frequenti
Can I take Acitretin with Norethindrone?
MediHelp rates the interaction as contraindicated. Acitretin and Norethindrone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Acitretin has been reported to interfere with progestin-only contraceptives, such as minipills, reducing their effectiveness. Since acitretin is highly teratogenic, any contraceptive failure is serious. Labeling advises against progestin-only pills in this setting.
How serious is the interaction between Acitretin and Norethindrone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not rely on norethindrone-only contraception during acitretin therapy. Use two reliable contraceptive methods, such as a combined hormonal method plus a barrier method, as advised by labeling.
What other medicines interact with Acitretin?
MediHelp also lists interactions of Acitretin with, for example, Demeclocycline, Doxycycline, Ethanol. The full list is on the Acitretin page.
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